Heat-stable drug could protect thousands of women from post-childbirth bleeding

Carbetocin could be a viable alternative to oxycotin to avoid excessive bleeding after birth, a study published in theNew England Journal of Medicine reports.Reuters
Source: Society for Endocrinology - Category: Endocrinology Source Type: news

Related Links:

Authors: Dhamane AD, Baker CL, Rajpura J, Mardekian J, Dina O, Russ C, Rosenblatt L, Lingohr-Smith M, Lin J Abstract Objective: To compare the risk of hospitalization and costs associated with major bleeding (MB) or stroke/systemic embolism (SE) among elderly patients with nonvalvular atrial fibrillation (NVAF) who initiated apixaban then switched to another oral anticoagulant (OAC) vs. those who continued with apixaban treatment. Methods: NVAF patients (≥65 years) initiating apixaban were identified from the Humana database (1/1/2013-9/30/2017) and grouped into Switcher and Continuer cohorts. For Switchers, the...
Source: Current Medical Research and Opinion - Category: Research Tags: Curr Med Res Opin Source Type: research
Conclusions: Trans-apical off-pump MV repair with the NeoChord system is a safe, minimally invasive procedure, with few minor complications. In well-selected candidates it provides successful treatment of degenerative MR. Results are anatomy dependent, so preoperative patient selection is crucial. PMID: 31119000 [PubMed]
Source: Videosurgery and Other Miniinvasive Techniques - Category: Surgery Tags: Wideochir Inne Tech Maloinwazyjne Source Type: research
Conclusions: We believe that uniportal VATS is a safe, feasible, and effective technique for selected bronchiectasis patients. PMID: 31118998 [PubMed]
Source: Videosurgery and Other Miniinvasive Techniques - Category: Surgery Tags: Wideochir Inne Tech Maloinwazyjne Source Type: research
Conclusions: Laparoscopic total mesorectal excision using the intersphincteric approach through the sacrococcygeal incision is feasible for treating patients with a contracted pelvis and super-low rectal carcinoma. PMID: 31118985 [PubMed]
Source: Videosurgery and Other Miniinvasive Techniques - Category: Surgery Tags: Wideochir Inne Tech Maloinwazyjne Source Type: research
Conclusions: The LSEGDS is a safe and effective procedure for management of cirrhotic portal hypertension, especially in patients with visible paraesophageal veins. PMID: 31118982 [PubMed]
Source: Videosurgery and Other Miniinvasive Techniques - Category: Surgery Tags: Wideochir Inne Tech Maloinwazyjne Source Type: research
In this study, we evaluated the incidence of postoperative bleeding, hematoma formation, and wound dehiscence after perioperative aspirin ingestion before foot and ankle surgery. The medical records of 379 patients treated over a 3-year period were reviewed. Patient demographics, surgical procedures, affected limbs (right foot versus left foot), anatomical surgical sites (forefoot, midfoot, and rearfoot), and week 2 surgical site inspection data were recorded. Mean patient age was 60.12 (range 21 to 81) years, and the overall wound complication rate was 0.80%. The patients were classified into 2 groups: those who took 81 m...
Source: The Journal of Foot and Ankle Surgery - Category: Orthopaedics Source Type: research
Caplacizumab-yhdp (Cablivi) is the first drug specifically indicated for acquired thrombotic thrombocytopenic purpura, a rare and potentially life-threatening blood clotting disorder. It is prescribed in combination with plasmapheresis and immunosuppressive therapy.The drug carries a warning that severe bleeding can occur with use, although the most common adverse effects are headache and minor bleeding from the nose or gums.Caplacizumab-yhdp is given initially as an iv bolus and then as a subcutaneous injection along with plasmapheresis.
Source: AJN - Category: Nursing Tags: Drug Watch Source Type: research
Publication date: 25–31 May 2019Source: The Lancet, Volume 393, Issue 10186Author(s): Inbar Raber, Cian P McCarthy, Muthiah Vaduganathan, Deepak L Bhatt, David A Wood, John G F Cleland, Roger S Blumenthal, John W McEvoySummaryAspirin is one of the most frequently used drugs worldwide and is generally considered effective for the secondary prevention of cardiovascular disease. By contrast, the role of aspirin in primary prevention of cardiovascular disease is controversial. Early trials evaluating aspirin for primary prevention, done before the turn of the millennium, suggested reductions in myocardial infarction and ...
Source: The Lancet - Category: General Medicine Source Type: research
ConclusionThe hemorrhoidal dearterialization technique presents good results, with light and easy-to-resolve complications and little postoperative pain.ResumoIntroduçãoO tratamento da doença hemorroidária pelas técnicas convencionais cursa com significante redução da qualidade de vida do doente, principalmente relacionada à dor pós-operatória e ao considerável tempo de afastamento do trabalho. A técnica de desarterialização hemorroidária associada à mucopexia retal é uma opção cirúrgi...
Source: Journal of Coloproctology - Category: Gastroenterology Source Type: research
Publication date: Available online 28 April 2019Source: Journal of Clinical and Experimental HepatologyAuthor(s): Atul Gawande, Gaurav K. Gupta, Ankit Gupta, Shashank J. Wanjari, Vasudha Goel, Vinay Rathore, Hemendra Bhardwaj, Sandeep NijhawanBackground and AimsThe present study is planned to assess etiologies, course, and outcome in patients with acute-on-chronic liver failure (ACLF).MethodsTwo hundred and eight (182 males and 26 females) patients of ACLF fulfilling modified Asia Pacific Association For Study Of Liver Consensus criteria 2009 admitted to the gastroenterology department of SMS Medical College and hospital, ...
Source: Journal of Clinical and Experimental Hepatology - Category: Gastroenterology Source Type: research
More News: Bleeding | Endocrinology | Study | Women