Fatigue is underestimated symptom of endometriosis

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Source: OnMedica Latest News - Category: UK Health Source Type: news

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In this study, epigenome-wide patterns of methylation were measured in schizophrenia suicide attempters (n = 54) and in schizophrenia non suicide attempters (n = 69) using DNA extracted from white blood cells. Analyses focused on identifying differentially methylated CpG sites and gene regions between attempters and non-attempters. We identified the CpG site cg19647197 within the CCDC53 gene, which is characterized by hypomethylation of WBC in schizophrenia attempters compared to non-attempters. Our results suggest that there is variation in DNA methylation associated with suicide attempt that may offer novel highl...
Source: Journal of Psychiatric Research - Category: Psychiatry Source Type: research
ConclusionsThere was no evidence that neither short-term nor long-term exposure to meteorological parameters or air pollen counts were associated with self-reported peripartum depressive symptoms in Uppsala, Sweden.
Source: European Psychiatry - Category: Psychiatry Source Type: research
Abstract The purpose of this review is to summarize current knowledge about the gut microbiota in neuropsychiatric disorders. It is estimated that the human gut is colonized by up to 1018 microorganisms, mostly anaerobic bacteria. The gut microbiome is responsible for multiple functions, e.g. tightness of the intestine barrier, digestion and absorption. The correlation between gut dysbiosis and development of psychiatric, autoimmune and allergic diseases as well as bidirectional communication between brain and gut microflora have been shown. Recent findings suggest that specific bacteria can be involved in the dev...
Source: Acta Neurobiologiae Experimentalis - Category: Neurology Authors: Tags: Acta Neurobiol Exp (Wars) Source Type: research
Publication date: Available online 19 July 2018Source: NeuronAuthor(s): Xiang Nie, Shiho Kitaoka, Kohei Tanaka, Eri Segi-Nishida, Yuki Imoto, Atsubumi Ogawa, Fumitake Nakano, Ayaka Tomohiro, Kazuki Nakayama, Masayuki Taniguchi, Yuko Mimori-Kiyosue, Akira Kakizuka, Shuh Narumiya, Tomoyuki FuruyashikiSummaryRepeated environmental stress has been proposed to induce neural inflammation together with depression and anxiety. Innate immune receptors, such as Toll-like receptors (TLRs), are activated by exogenous or endogenous ligands to evoke inflammation. Here we show that the loss of TLR2 and TLR4 (TLR2/4) abolished repeated so...
Source: Neuron - Category: Neuroscience Source Type: research
This study aimed to evaluate the effects of lorcaserin on body weight, cardiovascular risk factors, and safety in obese patients in Taiwan.MethodsIn this double-blind, randomised controlled trial, 171 obese adults were assigned to receive lorcaserin at a dose of 10 mg, or placebo, twice a day for 24 weeks. Diet and exercise counselling were given to all patients through the treatment period. Primary outcomes were proportion of patients achieving at least 5% and 10% reduction in body weight and mean change in body weight. Safety and tolerability endpoints such as Beck Depression Inventory-II, blood biochemistry, v...
Source: Obesity Research and Clinical Practice - Category: Eating Disorders & Weight Management Source Type: research
Hospitals across the country are reporting significant shortages of pain medication. A survey of anesthesiologists found that 95 percent say it is impacting patient care.(Image credit: Rick Bowmer/AP)
Source: NPR Health and Science - Category: Consumer Health News Authors: Source Type: news
ConclusionsBDI-II scores were significantly higher following 24 months of nitisinone therapy in patients that were followed up, however the majority of these patients remained in the minimal category of depression. Serum tyrosine and urinary 3-MT increased significantly following treatment with nitisinone. In contrast urinary 5-HIAA did not decrease consistently over the same period studied. Together these findings suggest nitisinone does not cause depression despite some observed effects on monoamine neurotransmitter metabolism.
Source: Molecular Genetics and Metabolism - Category: Genetics & Stem Cells Source Type: research
ConclusionsObesity appears to be associated with a negative impact on health-related quality of life, affecting the physical area more significantly than the psychosocial.ResumenAntecedentesLa calidad de vida relacionada con la salud es un elemento importante en la valoración integral del sobrepeso y la obesidad.ObjetivoEvaluar el impacto de la obesidad y la ganancia de peso sobre la calidad de vida relacionada con la salud en la cohorte dinámica Seguimiento Universidad de Navarra.Materiales y métodosLos análisis incluyeron a 10.033 participantes de la cohorte dinámica prospectiva del Pro...
Source: Revista Clinica Espanola - Category: Internal Medicine Source Type: research
BACKGROUND: suicide is a major public health issue in China. However, research on the impact of absolute and relative economic stats on suicide is scarce among the Chinese population, particularly rural young adults. Using a case-control psychological auto...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Young Adults Source Type: news
This study's objectives were to: 1) report state training requirements for pharmacist suicide education; and 2) d...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Program and Other Evaluations, Effectiveness Studies Source Type: news
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