Preclinical assessment of safety and efficacy of intravenous delivery of autologous adipose-derived regenerative cells (ADRCs) in the treatment of severe thermal burns using a porcine model

Burns are traumatic acute wounds which can be life-threatening. Despite improvement in burn wound care, severe burns are associated with high morbidity and disability [1,2]. For partial thickness and full thickness burns, acute burn management involves multiple activities including protecting the wound from further injury, initial cleansing and debridement, and determination of dressings with or without a topical antimicrobial agent [3,4]. Fluid resuscitation, prevention of hypothermia and pain management are also critical aspects of burn care and management [2,5].
Source: Burns : Journal of the International Society for Burn Injuries - Category: Cosmetic Surgery Authors: Source Type: research