Pregnancy Outcomes after Exposure to Certolizumab Pegol: Updated Results from a Pharmacovigilance Safety Database

Arthritis&Rheumatology,Volume 0, Issue ja, -Not available-.
Source: Arthritis and Rheumatology - Category: Rheumatology Authors: Source Type: research

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We present two identical twin sarcoidosis patients with carpal tunnel syndrome. A number of factors may cause carpal tunnel syndrome like wrist anatomy, occupation, diabetes, rheumatoid arthritis, pregnancy and renal failure. Although the above factors do not directly cause carpal tunnel syndrome, they may increase your chances of developing or aggravate median nerve damage as it is in sarcoidosis. Sarcoidosis relevant neuropathy and granulomas may be the primary mechanism of sarcoidosis associated carpal tunnel syndrome. Although rare, carpal tunnel syndrome may be a feature of sarcoidosis that may lead to irreversib...
Source: Monaldi Archives for Chest Disease - Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research
Authors: Andreoli L, García-Fernández A, Chiara Gerardi M, Tincani A Abstract BACKGROUND: Rheumatic diseases commonly affect women of childbearing age, when women may be contemplating pregnancy or they discover an unplanned pregnancy. Therefore, specific issues about pregnancy planning and management are commonly encountered in patients during these times. Knowledge of the effect of pregnancy on disease activity is important for counseling. This review summarizes recent data on the course of different rheumatic diseases during pregnancy and the postpartum period. Rheumatoid arthritis and systemic lupu...
Source: The Israel Medical Association Journal - Category: General Medicine Tags: Isr Med Assoc J Source Type: research
This article has critically evaluated the research published after the 9th European Workshop in Periodontology in November 2012 to ascertain whether recent research has affected the merit of the manifesto. It was found that recent research supports the manifesto regarding diabetes mellitus, cardiovascular disease and adverse pregnancy outcomes, although further high-quality randomised controlled trials are required to support the manifesto statement that "certain populations of pregnant women may benefit from periodontal therapy." Furthermore, there is now good evidence from systematic reviews for an association ...
Source: Journal of the International Academy of Periodontology - Category: Dentistry Tags: J Int Acad Periodontol Source Type: research
Introduction: Psoriasis (PSO) and psoriatic arthritis (PsA) often affect women of childbearing age; but it is unclear if these women ( ♀) feel able to make informed treatment decisions around pregnancy and breastfeeding. This survey gained insight on disease management and pregnancy, to assess if they feel adequately supported. Methods: Women (18–45 years) with chronic inflammatory diseases from the US, Japan, and Germany, Fran ce, UK, Italy and Spain (EU5) participated in a 20-min online survey (Jul–Oct 2017; InSites Consulting).
Source: Journal of the American Academy of Dermatology - Category: Dermatology Source Type: research
Two Novel Technologies for the Detection of Anti-cardiolipin and Anti β2-Glycoprotein Antibodies in the Real Life: Chemiluminescent in Comparison to the Addressable Laser Bead Immunoassays. Immunol Invest. 2019 Aug 12;:1-11 Authors: Grossi V, Infantino M, Benucci M, Li Gobbi F, Bandinelli F, Damiani A, Bodio C, Borghi MO, Mahler M, Aure MA, Bentow C, Manfredi M Abstract In the present study, we evaluated two novel technologies, the chemiluminescent immunoassay (CIA) QUANTA Flash on BIO-FLASH (Inova Diagnostics, San Diego, CA, USA) and the addressable laser bead immunoassay (ALBIA) on BioPlex&trade...
Source: Immunological Investigations - Category: Allergy & Immunology Tags: Immunol Invest Source Type: research
AbstractThe Kuwait Association of Rheumatology (KAR) aimed to develop a set of recommendations for the treatment of patients with rheumatoid arthritis (RA), tailored to the unique patient population and healthcare system of Kuwait. Each recommendation was developed based on expert opinion and evaluation of clinical practice guidelines from other international and national rheumatology societies. Online surveys were conducted to collate feedback on each KAR member ’s level of agreement (LoA) with definitions of disease-/treatment-related terms used and the draft recommendations. Definitions/recommendations achieving a...
Source: Rheumatology International - Category: Rheumatology Source Type: research
Pregnant women with inflammatory arthritis may have an increased risk for preterm delivery. New research examined the risk of preterm delivery and other pregnancy complications in women with RA and JIA vs. healthy controls...
Source: The Rheumatologist - Category: Rheumatology Authors: Tags: Conditions Rheumatoid Arthritis Arthritis Care & Research juvenile idiopathic arthritis (JIA) pregnancy pregnancy complications pregnant women preterm birth Rheumatoid Arthritis (RA) Source Type: research
AbstractRituximab (RTX) is an approved treatment for rheumatoid arthritis (RA) patients that do not respond adequately to disease-modifying antirheumatic drugs. However, different new concerns, such as efficacy, optimum dose, safety issues, prediction of response to RTX, and pregnancy outcomes have attracted a lot of attention. The PubMed database was systematically reviewed for the last published articles, new findings, and controversial issues regarding RTX therapy in RA using “Rheumatoid arthritis” AND “rituximab” keywords, last updated on June 18, 2019. From 1812 initial recorders, 162 studies m...
Source: Clinical Rheumatology - Category: Rheumatology Source Type: research
The end of another quarter means a new list of FDA-approved drugs for primary care. Which ones should you know about? Click through to find out.  
Source: ConsultantLive - Category: Internal Medicine Authors: Tags: Obesity Opioid Related Disorders Osteoporosis Pregnancy and Birth Psoriasis Rheumatoid Arthritis T2 Diabetes Source Type: news
This study confirms meta-analyses of smaller studies in the United States that suggest that cesarean section deliveries are risk factors for development of allergy and autoimmune disease. Elective cesarean section deliveries have increased from 5% in 1970 to 25% in 2010 in the US, while at the same time the incidence of autoimmune diseases has increased in Western society over the last several decades, and there may be a correlation. Altered intestinal colonization in medically-indicated vs. elective cesarean sections We have learned that major changes in intestinal colonization occur after elective cesarean sections (thos...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Digestive Disorders Family Planning and Pregnancy Probiotics Women's Health Source Type: blogs
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