Open ‐Label Non‐Mandatory Transitioning From Originator Etanercept to Biosimilar SB4: 6‐Month Results From a Controlled Cohort Study

Arthritis&Rheumatology,Volume 0, Issue ja, -Not available-.
Source: Arthritis and Rheumatology - Category: Rheumatology Authors: Source Type: research

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Publication date: December 2019Source: Journal of Functional Foods, Volume 63Author(s): Min-Sung Kwon, Mi-Young Shin, Seul Ki Lim, Jieun Lee, Hyo Kyeong Park, Namhee Kim, Misun Yun, Hee Eun Jo, Young Joon Oh, Hak-Jong ChoiAbstractRheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammation, which can cause severe bone and joint damage. Leuconostoc citreum WiKim56 is a lactic acid bacterium isolated from gatkimchi, fermented mustard leaves. We evaluated the ability of Leu. citreum WiKim56 to modulate T cell responses and suppress RA in a mouse model of collagen-induced arthritis. Leu. citreum WiK...
Source: Journal of Functional Foods - Category: Nutrition Source Type: research
Publication date: Available online 20 September 2019Source: Reumatología Clínica (English Edition)Author(s): Susana Aideé González-Chávez, César Pacheco-Tena, Rosa María Campos Torres, Celia María Quiñonez-Flores, Greta Reyes-Cordero, Teresita de Jesús Caraveo FrescasAbstractObjectiveTo characterize the orofacial abnormalities in patients with rheumatoid arthritis (RA) and compare them with those in a reference population.MethodsThe study included 30 RA patients and 30 consecutive patients in an odontology clinic in whom RA was ruled out. Patients underw...
Source: Reumatologia Clinica - Category: Rheumatology Source Type: research
Conclusions: Collectively, given its sensitivity with low cell numbers and avoidance of radioactive substrates, UHPLC-MS/MS–based analysis of FPGS activity may be eligible for routine therapeutic drug monitoring of MTX in RA and leukemia for therapy (non)response evaluations.
Source: Therapeutic Drug Monitoring - Category: Drugs & Pharmacology Tags: Original Article Source Type: research
AbstractRheumatoid arthritis (RA) is a chronic disabling disease that is associated with increased localized and generalized osteoporosis (OP). Previous studies estimated that approximately one-third of the RA population experience bone loss. Moreover, RA patients suffer from a doubled fracture incidence depending on several clinical factors, such as disease severity, age, glucocorticoid (GC) use, and immobility. As OP fractures are related to impaired quality of life and increased mortality rates, OP has an enormous impact on global health status. Therefore, there is an urgent need for a holistic approach in daily clinica...
Source: Drugs and Aging - Category: Geriatrics Source Type: research
We describe the first case of 2 consecutive acute septic arthritis infections of both knees caused by the same virulent strain of Kingella kingae belonging to the virulent sequence type complex 14, in a 16-month-old boy. Both infections occurred after viral upper respiratory tract infections.
Source: The Pediatric Infectious Disease Journal - Category: Infectious Diseases Tags: Brief Reports Source Type: research
Rheumatology professional and patients visited with 117 legislators and their staffs during the 2019 Advocates for Arthritis event to champion better rheumatology patient care and access.
Source: The Rheumatologist - Category: Rheumatology Authors: Tags: Legislation & Advocacy Advocacy 101 Advocates for Arthritis RheumPAC Source Type: research
CONCLUSION: DAS28 score and disease activity are strong indicators of TMJ affection in RA patients when compared to RF and ACCP. ACCP is a better indicator of changes in condylar measurements than TMJ osteoarthritic changes. While RF is the least efficient indicator of TMJ involvement in RA patients. PMID: 31530023 [PubMed - as supplied by publisher]
Source: Dentomaxillofacial Radiology - Category: Radiology Tags: Dentomaxillofac Radiol Source Type: research
Authors: Ciccacci C, Latini A, Perricone C, Conigliaro P, Colafrancesco S, Ceccarelli F, Priori R, Conti F, Perricone R, Novelli G, Borgiani P Abstract Autoimmune diseases (AIDs) are complex diseases characterized by persistent or recurrent inflammation, alteration of immune response, and production of specific autoantibodies. It is known that different AIDs share several susceptibility genetic loci. Tumor necrosis factor alpha inducible protein 3 (TNFAIP3) encodes the ubiquitin-modifying enzyme A20, which downregulates inflammation by restricting NF-κB, a transcription factor that regulates expression of var...
Source: Journal of Immunology Research - Category: Allergy & Immunology Tags: J Immunol Res Source Type: research
Publication date: Available online 19 September 2019Source: Chemico-Biological InteractionsAuthor(s): Prachurjya Dutta, Ravi Kumar Sahu, Tapan Dey, Manisha Datta Lahkar, Prasenjit Manna, Jatin KalitaAbstractInsect-based bioactive components are emerging as novel sources of drugs, effective against various diseases. Inflammation is considered to be an innate immune response developed by different organisms against foreign pathogens and cellular stress. However, repetitive elevated inflammation is considered to be responsible for development of many other diseases including colitis and arthritis. Due to the limited activitie...
Source: Chemico Biological Interactions - Category: Biochemistry Source Type: research
If you’re like most people, you’ve seen a ton of direct-to-consumer (DTC) drug ads in recent years. They’re all over television, in magazines, online, on billboards, and slapped on the sides of buses, promoting treatments for arthritis, cancer, heartburn, psoriasis, flagging memory — and more. The deluge of drug ads can be overwhelming. Worse, the information is often incomplete, biased, or confusing. That’s why we’re launching the Harvard Health Ad Watch series to highlight some benefits and problems with health product advertisements. We’ll focus on the evidence behind the ads an...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Children's Health Drugs and Supplements Men's Health Women's Health Source Type: blogs
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