SNMMI: Early prostate cancer therapy extends lives

PHILADELPHIA - Providing lutetium-177 prostate-specific membrane antigen radioligand...Read more on AuntMinnie.comRelated Reading: Annals: Overdiagnosis must be better defined SNMMI: New therapy aids patients with neuroendocrine tumors SNMMI: AI can predict survival in sarcoma patients SNMMI 2018: A year of promotion and ongoing challenges Faster MRI protocol avoids unneeded prostate biopsies
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news

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Publication date: Available online 19 July 2018Source: Life SciencesAuthor(s): Amr Ahmed El-Arabey, Salama Abdu Salama, Adel Rashad Abd-AllahAbstractIn 2015, more than 1.6 million new cancer cases with 589,430 deaths were estimated over worldwide. Cancer is a complex disease with abnormal cell growth control which is hallmarked by chromosome misalignment and consequently genomic instability. Mitosis is a well-known target for chemotherapy as taxol and colchicines inhibit tumor cell division by inhibiting mitotic spindle plasticity. Accumulating evidence has revealed that the Centromere-associated protein E (CENP-E) is expr...
Source: Life Sciences - Category: Biology Source Type: research
Publication date: Available online 19 July 2018Source: Life SciencesAuthor(s): Mohammad Rasheduzzaman, Jae-Kyo Jeong, Sang-Youel ParkAbstractAimsTRAIL is a promising anticancer agent that has the potential to sensitize a wide variety of cancer or transformed cells by inducing apoptosis. However, resistance to TRAIL is a growing concern. Current manuscript aimed to employing combination treatment to investigate resveratrol induced TRAIL sensitization in NSCLC.MethodA549 and HCC-15 cells were used in experimental design. Cell viability was determined by morphological image, crystal violet staining and MTT assay. Apoptosis wa...
Source: Life Sciences - Category: Biology Source Type: research
Publication date: Available online 19 July 2018Source: Life SciencesAuthor(s): Yawei Shi, Yang Zhao, Yunjian Zhang, NiJiati AiErken, Nan Shao, Runyi Ye, Ying Lin, Shenming WangAbstractAimsBreast cancer is the major diagnosed cancer and the leading reason of cancer related death among women, and the tumor size is one of the risk factors. Therefore, it is significant to reveal the principle of breaking the subtle homeostasis of cell cycle and sustaining chronic proliferation of cancer cells.Main methodsThe expression of TNNT1 was examined by qPCR and western blotting. The effect of TNNT1 on cell proliferation was detected by...
Source: Life Sciences - Category: Biology Source Type: research
Publication date: September 2018Source: Biomedical Signal Processing and Control, Volume 46Author(s): Supriya Patil, Gourish Naik, Radhakrishna Pai, Rajendra GadAbstractInvention of the microarray technology has rendered it possible to inspect the whole genome at once in cancer classification. However, in order to curtail the computational complexity and augment the accuracy of cancer classification, it is essential to sift the vast microarray data for the informative genes. In this paper, Thresholding and Ratio methods are presented, individually as well as conjointly (hybrid method) to choose optimal gene subset from the...
Source: Biomedical Signal Processing and Control - Category: Biomedical Science Source Type: research
We present a quantitative study of the performance of two automatic methods for the early detection of ovarian cancer that can exploit longitudinal measurements of multiple biomarkers. The study is carried out for a subset of the data collected in the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS). We use statistical analysis techniques, such as the area under the Receiver Operating Characteristic (ROC) curve, for evaluating the performance of two techniques that aim at the classification of subjects as either healthy or suffering from the disease using time-series of multiple biomarkers as inputs. The first ...
Source: Biomedical Signal Processing and Control - Category: Biomedical Science Source Type: research
Publication date: September 2018Source: Advances in Medical Sciences, Volume 63, Issue 2Author(s): Thomas J. Humphries, Brittny Rule, Augustina Ogbonnaya, Michael Eaddy, Orsolya Lunacsek, Lois Lamerato, Jennifer PocoskiAbstractPurposePrevious retrospective claims database analyses reported increased prevalence and earlier onset of cardiovascular comorbidities in patients with versus without hemophilia A. A comprehensive chart review was designed to further investigate previous findings.MethodsThis retrospective chart review study was conducted at Henry Ford Health System (Detroit, MI, USA). Baseline demographics, bleeding ...
Source: Advances in Medical Sciences - Category: Biomedical Science Source Type: research
In conclusion, these results suggest the potential preventive effects of the five phytochemicals on the promoting effect of Ni on human lung cancer cell invasion. In addition, the preventive effects are associated with downregulation of the TLR4/NF-κB signaling pathway, especially for quercetin and chrysin.
Source: Chemico Biological Interactions - Category: Biochemistry Source Type: research
PHILADELPHIA - Artificial intelligence (AI) analysis of stress SPECT myocardial...Read more on AuntMinnie.comRelated Reading: SNMMI: Early prostate cancer therapy extends lives SNMMI: New therapy aids patients with neuroendocrine tumors SNMMI: AI can predict survival in sarcoma patients SNMMI 2018: A year of promotion and ongoing challenges ASNC releases new guidelines for SPECT MPI
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
Conclusion: The cancer burden among PLWH is projected to shift, with prostate and lung cancer expected to emerge as the most common types by 2030. Cancer will remain an important comorbid condition, and expanded access to HIV therapies and cancer prevention, screening, and treatment is needed. Primary Funding Source: National Cancer Institute. PMID: 29801099 [PubMed - as supplied by publisher]
Source: Annals of Internal Medicine - Category: Internal Medicine Authors: Tags: Ann Intern Med Source Type: research
The objective of this study was to explore the cancer incidence rates among HIV-infected persons with commercial insurance who were on antiretroviral therapy and compare them with those rates in the general population. Paid health insurance claims for 63,221 individuals 18 years or older, with at least one claim with a diagnostic code for HIV and at least one filled prescription for an antiretroviral medication between January 1, 2006, and September 30, 2012, were obtained from the LifeLink® Health Plan Claims Database. The expected number of cancer cases in the general population for each gender-age group (60 years) w...
Source: Journal of Cancer Epidemiology - Category: Epidemiology Tags: J Cancer Epidemiol Source Type: research
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