Relievant Announces Completion of $58M Series E Financing to Support US Commercialization

Company to open corporate headquarters in Minneapolis, MN MINNEAPOLIS, June 26, 2018 -- (Healthcare Sales &Marketing Network) -- Relievant Medsystems, a privately-held medical device company developing minimally-invasive solutions for chronic low back ... Devices, Orthopaedic, Neurosurgery, Venture Capital Relievant Medsystems, low back pain, Intracept, basivertebral nerve
Source: HSMN NewsFeed - Category: Pharmaceuticals Source Type: news

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Thirty percent of Americans have low back pain (LBP) at any given time, leading to approximately 50 million physician visits in the U.S. annually. Chronic low back pain (CLBP) can be difficult to diagnose and treat using either non-surgical therapies or surgical interventions. Antonacci et al. proposed that some pain previously ascribed to the disc actually emanates from the vertebral endplate nociceptors which communicate to the CNS through the basivertebral nerve (BVN).1 The purpose of the present study is to report the 2-year clinical outcomes for CLBP patients treated with radiofrequency (RF) ablation of the BVN in a r...
Source: Journal of Vascular and Interventional Radiology : JVIR - Category: Radiology Authors: Tags: Scientific Session 21: I Got Your Back (Spinal Interventions) Source Type: research
DiscussionThis will be the first community-based trial to assess the benefits of exercise and education in the management of CLBP among adults in rural Nigeria. The study may provide a relatively inexpensive, assessable, and effective alternative intervention for reducing CLBP disability in a low-resource rural Nigerian community.
Source: Integrative Medicine Research - Category: Complementary Medicine Source Type: research
Conditions:   Chronic Low Back Pain;   Older Adults Intervention:   Device: acupuncture Sponsor:   McLean Center for Complementary and Alternative Medicine, PLC Completed
Source: - Category: Research Source Type: clinical trials
Musculoskeletal pain disorders (MDs), such as osteoarthritis, low back pain and neck pain, are common health problems and a major cause of disease burden worldwide.10,13 MDs are the second most frequent cause of disability, accounting for 21.3% of the total years lived with disability, second only to mental health conditions.47,67 Psychological factors are strongly associated with MDs,6,13,24,48 and are thought to play a role in the development of chronic MDs (defined as pain lasting longer than three months).
Source: The Journal of Pain - Category: Materials Science Authors: Tags: Review Article Source Type: research
Personal convictions in referral to pain cause misbeliefs in health professionals, which can influence patients who suffer from non-specific chronic low back pain. Likewise, health professionals ’ beliefs affec...
Source: BMC Family Practice - Category: Primary Care Authors: Tags: Study protocol Source Type: research
ConclusionsOur results suggest to use task ‐specific measures of pain‐related fear when assessing the relationship with movement. It would be of interest to investigate whether reducing task‐specific fear changes protective movement behavior.This article is protected by copyright. All rights reserved.
Source: European Journal of Pain - Category: Anesthesiology Authors: Tags: Original Article Source Type: research
In this study, individualized physical maneuvers were used to exacerbate clinical pain in patients with chronic low back pain (N = 53), thereby experimentally producing lower and higher pain states. Multivariate machine-learning models were then built from brain imaging (resting-state blood-oxygenation-level-dependent and arterial spin labeling functional imaging) and autonomic activity (heart rate variability) features to predict within-patient clinical pain intensity states (ie, lower vs higher pain) and were then applied to predict between-patient clinical pain ratings with independent training and testing data sets. Wi...
Source: Pain - Category: Anesthesiology Tags: Research Paper Source Type: research
We sought to replicate previous findings that low endogenous opioid (EO) function predicts greater morphine analgesia and extended these findings by examining whether circulating endocannabinoids and related lipids moderate EO-related predictive effects. Individuals with chronic low-back pain (n = 46) provided blood samples for endocannabinoid analyses, then underwent separate identical laboratory sessions under 3 drug conditions: saline placebo, intravenous (i.v.) naloxone (opioid antagonist; 12-mg total), and i.v. morphine (0.09-mg/kg total). During each session, participants rated low-back pain intensity, evoked heat pa...
Source: Pain - Category: Anesthesiology Tags: Research Paper Source Type: research
NEW YORK and INDIANAPOLIS, Feb. 19, 2019 -- (Healthcare Sales &Marketing Network) -- Pfizer Inc. (NYSE: PFE) and Eli Lilly and Company (NYSE: LLY) today announced positive top-line results from a Phase 3 study evaluating tanezumab in patients with modera... Biopharmaceuticals Eli Lilly, Pfizer, tanezumab, low back pain
Source: HSMN NewsFeed - Category: Pharmaceuticals Source Type: news
A non-opioid painkiller developed by Pfizer Inc and Eli Lilly and Co succeeded in reducing chronic low back pain when used in a stronger dose, results from a late-stage study showed on Tuesday.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
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