Workforce warning as government makes cancer pledge

The Royal College of Radiologists has urged the government to fund more training places for clinical oncologists, following data revealing that workforce shortages are set to worsen over the coming years.
Source: HSJ - Category: UK Health Source Type: news

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In this study, five population databases plus the Catalog of Somatic Mutations in Cancer was employed to demonstrate the impact of changing the PF cut-off on assignment of variants as germline versus somatic. The 1% to 2% PF cut-offs widely used in bioinformatic pipelines result in high sensitivity for classification of somatic variants, but unnecessarily reduced sensitivity for germline variants. Using optimized PF cut-offs, the source of variants in TCGA data could be predicted with>95% accuracy. Further exploration of four TCGA cancer datasets indicated that the optimal cut-off is influenced by both cancer type and t...
Source: The Journal of Molecular Diagnostics - Category: Pathology Source Type: research
Publication date: Available online 25 June 2019Source: The Journal of Molecular DiagnosticsAuthor(s): Paolo A. Ascierto, Carlo Bifulco, Giuseppe Palmieri, Solange Peters, Nikoletta SidiropoulosAn enduring goal of personalized medicine in cancer is the ability to identify patients who are likely to respond to specific therapies. Our growing understanding of the biology and molecular signatures of individual tumor types has facilitated the identification of predictive biomarkers and has led to an increasing number of diagnostic tests to be performed, often as serial and distinct assays on limited tumor specimens. The biomark...
Source: The Journal of Molecular Diagnostics - Category: Pathology Source Type: research
Objective The aim of this study was to use an electronic tablet–based education module to increase patient knowledge about human papillomavirus (HPV). Methods Patients presenting to an academic colposcopy clinic were first queried as to whether they had been infected with HPV. A quality improvement project was then conducted using a 4-question pretest assessing baseline knowledge about HPV and cancer, followed by a tablet-based education module and a 5-question posttest. Results Between June 2017 and January 2018, 119 patients participated in the tablet education. At their initial visit, only 50 (42.0%) of pa...
Source: Journal of Lower Genital Tract Disease - Category: OBGYN Tags: Original Research Articles: Cervix and HPV Source Type: research
Conclusions Both methods of sampling were found to be acceptable to women. Self-sampling is cost-effective and could increase the screening coverage among underscreened populations. However, more information about the quality, reliability, and accuracy of self-sampling is needed to increase women's confidence about using to this method.
Source: Journal of Lower Genital Tract Disease - Category: OBGYN Tags: Original Research Articles: Cervix and HPV Source Type: research
No abstract available
Source: Journal of Lower Genital Tract Disease - Category: OBGYN Tags: Forum Source Type: research
Nashville-based E+CancerCare (stylized e+CancerCare) has been sold to a Newport Beach, California, company, according to a news release. Integrated Oncology Network LLC, a portfolio company of Silver Oak Services Partners LLC, announced Wednesday it has bought E+CancerCare. Terms of the deal were not disclosed. Founded in 2002, E+CancerCare operates 21 outpatient cancer treatment centers in 21 states, according to the release. The company’s centers provide diagnostic testing, radiation oncology…
Source: Health Care:Pharmaceuticals headlines - Category: Pharmaceuticals Authors: Source Type: news
ConclusionIt seems that human breast cancer and BLV infection in cattle could be associated using nested PCR technique.
Source: Microbial Pathogenesis - Category: Infectious Diseases Source Type: research
ConclusionsMore research is necessary to understand why cervical cancer screenings are not associated with receipt of an AFV.
Source: American Journal of Infection Control - Category: Infectious Diseases Source Type: research
Conclusions Group C, F, and G streptococci are common pathogens in patients with an underlying malignancy, particularly solid tumor malignancies. Their usual association with other pathogens furthers the need for combinatorial therapeutic strategies to combat polymicrobial infections.
Source: Infectious Diseases in Clinical Practice - Category: Infectious Diseases Tags: Original Articles Source Type: research
Conclusions: Although KS incidence rates have decreased nationally, age, racial, and geographic disparities persist, including increasing risk among younger Black men and particularly elevated rates in some southern states and urban areas. Further research is needed to address racial and geographic AIDS-related KS disparities.
Source: JAIDS Journal of Acquired Immune Deficiency Syndromes - Category: Infectious Diseases Tags: Epidemiology Source Type: research
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