A pill to deliver insulin for type-1 diabetics

Scientists have developed a new pill that could give type-1 diabetes patients an alternative to insulin injections, according to a study published in theProceedings of the National Academy of Sciences.Science Daily
Source: Society for Endocrinology - Category: Endocrinology Source Type: news

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Publication date: January–February 2019Source: Diabetes &Metabolic Syndrome: Clinical Research &Reviews, Volume 13, Issue 1Author(s): Sin Yee Tan, Joyce Ling Mei Wong, Yan Jinn Sim, Su Sie Wong, Safa Abdelgadir Mohamed Elhassan, Sean Hong Tan, Grace Pei Ling Lim, Nicole Wuen Rong Tay, Naveenya Chetty Annan, Subrat Kumar Bhattamisra, Mayuren CandasamyAbstractType 1 and type 2 diabetes mellitus is a serious and lifelong condition commonly characterised by abnormally elevated blood glucose levels due to a failure in insulin production or a decrease in insulin sensitivity and function. Over the years, prevalence ...
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - Category: Endocrinology Source Type: research
AbstractAimsSome patients with diabetic ketoacidosis develop cerebral edema (CE) in the course of type 1 diabetes mellitus (T1D), which may result in central nervous system disorders and high mortality. The imperfection of existing neuroimaging techniques for early recognition of CE forces us to search for the new and non-invasive methods. The aim of the study was to assess the usefulness of new methods (pachymetry, transorbital ultrasonography —USG, optical coherence tomography—OCT study) in the assessment of the risk of CE occurrence in children with newly diagnosed T1D.MethodsThe study group included 50 chil...
Source: Acta Diabetologica - Category: Endocrinology Source Type: research
Type 1 diabetes (T1D) is an autoimmune disease in which insulin-producing beta cells, found within the islets of Langerhans in the pancreas, are destroyed by islet-infiltrating T cells. Identifying the antigenic targets of beta-cell reactive T cells is critical to gain insight into the pathogenesis of T1D and develop antigen-specific...
Source: Proceedings of the National Academy of Sciences - Category: Science Authors: Tags: Biological Sciences Source Type: research
AbstractPurposeTo clarify the relevance between smoking and diabetic retinopathy in patients with type 1 and type 2 diabetes mellitus.MethodsPublished evidence were searched in MEDLINE and EMBASE from the databases began until Feb. 2017. Studies evaluating the association between smoking and diabetic retinopathy or evaluating the risk factors of diabetic retinopathy including smoking were included.ResultsTotally 73 studies were identified, among which 19 studies included type 1 diabetes patients and 56 studies included type 2 diabetes patients. In type 1 diabetes, compare with non-smokers, the risk of diabetic retinopathy ...
Source: Endocrine - Category: Endocrinology Source Type: research
Journal of Diabetes,Volume 0, Issue ja, -Not available-.
Source: Journal of Diabetes - Category: Endocrinology Authors: Source Type: research
Publication date: Available online 13 October 2018Source: Trends in Endocrinology &MetabolismAuthor(s): Rinke Stienstra, Mihai G. NeteaIn addition to the impact of Bacillus Calmette–Guerin (BCG) vaccination on antimicrobial host defence, a novel study reveals beneficial effects on glycaemic control in patients with long-standing type 1 diabetes mellitus (T1DM). These effects are ascribed to an accelerated glucose consumption in immune cells due to increased glycolysis and reduced oxidative phosphorylation.
Source: Trends in Endocrinology and Metabolism - Category: Endocrinology Source Type: research
Journal of Cellular Physiology, EarlyView.
Source: Journal of Cellular Physiology - Category: Cytology Authors: Source Type: research
Journal of Cellular Physiology, EarlyView.
Source: Journal of Cellular Physiology - Category: Cytology Authors: Source Type: research
The objective of this nationwide population-based cohort study was to evaluate the correlation between continuous glucose monitoring (CGM) use and glucose variability in pre-schoolers with type 1 diabetes.
Source: Diabetes Research and Clinical Practice - Category: Endocrinology Authors: Source Type: research
CONCLUSION: T1DM may be more common in Korean adults than previously believed. Metabolic syndrome may be a frequent finding in individuals with T1DM in Korea. PMID: 30302960 [PubMed - as supplied by publisher]
Source: Diabetes and Metabolism Journal - Category: Endocrinology Tags: Diabetes Metab J Source Type: research
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