Sustained and repeated mouth opening leads to development of painful temporomandibular disorders involving macrophage/microglia activation in mice

This study suggests that mouth opening for an extended period during dental treatments or oral intubations may risk the development of chronic TMD and inflammation associated with macrophage and microglia in the tissue and trigeminal system contributes to the development of TMD pain.
Source: Pain - Category: Anesthesiology Tags: Research Paper Source Type: research

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CONCLUSION: The etiology of chronic groin pain post hernia repair is related in part to nerve injury. This is supported by the high frequency of sensory symptoms and numbness in these patients. However other factors including the role of tissue injury and inflammatory postoperative changes need to be considered. KEY WORDS: Chronic postoperative pain, Inguinal hernia repair, Open surgery, Laparoscopic surgery. PMID: 31719216 [PubMed - as supplied by publisher]
Source: Annali Italiani di Chirurgia - Category: Surgery Tags: Ann Ital Chir Source Type: research
Abstract The Editor-in-Chief has retracted this article [1] because an investigation by Keio University has concluded that there are inaccuracies in the data reported. PMID: 31730223 [PubMed - in process]
Source: Aging Clinical and Experimental Research - Category: Geriatrics Authors: Tags: Aging Clin Exp Res Source Type: research
Publication date: Available online 16 November 2019Source: Artificial Intelligence in MedicineAuthor(s): Anam Mustaqeem, Syed Muhammad Anwar, Muhammad MajidAbstractIn the last few years, hospitals have been collecting a large amount of health related digital data for patients. This includes clinical test reports, treatment updates and disease diagnosis. The information extracted from this data is used for clinical decisions and treatment recommendations. Among health recommender systems, collaborative filtering technique has gained a significant success. However, traditional collaborative filtering algorithms are facing ch...
Source: Artificial Intelligence in Medicine - Category: Bioinformatics Source Type: research
Publication date: Available online 15 November 2019Source: Fuß &SprunggelenkAuthor(s): Hubert Hörterer, Sebastian Felix Baumbach, Mareen Braunstein, Ulrike Szeimies, Wolfgang Böcker, Markus Walther, Hans PolzerZusammenfassungSchmerzen am Ansatz der Achillessehne stellen mit einer Lebenszeitinzidenz von 6% ein häufiges Krankheitsbild dar. Mittels klinischer Untersuchung, Röntgen und MRT können die Pathologien entsprechend ihrer Lokalisation in drei verschiedene Kompartimente (retro-, intra-, prä-achillär) eingeteilt werden. Führt die konservative Therapie nicht zu einer ausr...
Source: Fuss and Sprunggelenk - Category: Podiatry Source Type: research
Conclusion: Pain, fatigue and dyspnoea did not seem to highly correlate with occupational performance or impact occupational performance over time of people with advanced cancer. PMID: 31729272 [PubMed - as supplied by publisher]
Source: Scandinavian Journal of Occupational Therapy - Category: Occupational Health Tags: Scand J Occup Ther Source Type: research
Summary: Orofacial pain syndromes encompass several clinically defined and classified entities. The focus here is on the role of clinical neurophysiologic and psychophysical tests in the diagnosis, differential diagnosis, and pathophysiological mechanisms of definite trigeminal neuropathic pain and other chronic orofacial pain conditions (excluding headache and temporomandibular disorders). The International Classification of Headache Disorders 2018 classifies these facial pain disorders under the heading Painful cranial neuropathies and other facial pains. In addition to unambiguous painful posttraumatic or postherpetic...
Source: Journal of Clinical Neurophysiology - Category: Neurology Tags: Invited Review Source Type: research
CONCLUSION: Dysregulated psychophysiologic interactions may affect the development of tinnitus in patients with chronic TMD. PMID: 31247060 [PubMed - as supplied by publisher]
Source: Journal of Orofacial Pain - Category: ENT & OMF Tags: J Oral Facial Pain Headache Source Type: research
Conclusion: Characteristics and nonverbal behaviors of experimenters/clinicians contribute to the elicitation and modulation of pain, placebo, and nocebo effects.IntroductionThe present qualitative review investigated whether the characteristics or nonverbal behavior (NB) of the person administrating painful stimulation affected pain or placebo/nocebo effects in the research participant. The placebo effect is a psychobiological response that may occur following the application of active and inactive interventions (1). Applying an inactive medication paired with positive information about its analgesic effects can reduce pa...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
“Buprenorphine is a kappa receptor antagonist. For these reasons, buprenorphine might be unique in its ability to treat chronic pain and possibly OIH.” The opioid crisis has been fueled by the use of opioids to treat chronic pain.  Practice patterns have changed, but doctors are still criticized for their roles in the overuse of opioids.  I’ve sat through community ‘heroin forums’ (sometimes on stage) as sheriffs, politicians, and ‘recovered addicts’ firmly pointed fingers at health professionals.  I, meanwhile, kept my finger under the table, but had the t...
Source: Suboxone Talk Zone - Category: Addiction Authors: Tags: Acute Pain Buprenorphine Chronic pain Suboxone treatment buprenorphine treats chronic pain chronic pain treatment opioid induced hyperalgesia opioid pain relief pain vs. addiction Source Type: blogs
CONCLUSIONS: Unfortunately most treating physicians are unaware of this defect of sympathetic nervous system hypofunction leading to the absorption of toxins, which when it involves brain tissue, leads to severe headaches. Thus, the gynecologist who is aware of this syndrome because sympathetic nervous system hypofunction is the most common cause of pelvic pain, may need to intervene in women with chronic headaches, even TMJ. PMID: 27048031 [PubMed - in process]
Source: Clinical and Experimental Obstetrics and Gynecology - Category: OBGYN Tags: Clin Exp Obstet Gynecol Source Type: research
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