Sensitivity and specificity of hypoactivations and failure of de-activation in schizophrenia

Brain functional changes reported in schizophrenia include reduced prefrontal cortex activation (hypofrontality), increased frontal activation (hyperfrontality) and failure of de-activation in the medial frontal cortex. The relative importance of these changes is unestablished.

Source: Schizophrenia Research - June 25, 2018 Category: Psychiatry Authors: Pilar Salgado-Pineda, Joaquim Radua, Salvador Sarr ó, Amalia Guerrero-Pedraza, Raymond Salvador, Edith Pomarol-Clotet, Peter J. McKenna Source Type: research