Forecasting the effectiveness of indoor residual spraying for reducing dengue burden

ConclusionsUsing a detailed agent-based dengue transmission model for Yucat án State, Mexico, we predict that high coverage indoor residual spraying (IRS) interventions can largely eliminate transmission for a few years, when applied a few months before the typical seasonal epidemic peak. However, vector control succeeds by preventing infections, which precludes natural im munization. Thus, as a population benefits from mosquito control, it gradually loses naturally acquired herd immunity, and the control effectiveness declines; this occurs across all of our modeled scenarios, and is consistent with other empirical work. Long term control that maintains early effectiv eness would require some combination of increasing investment, complementary interventions such as vaccination, and control programs across a broad region to diminish risk of importation.
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research

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Authors: Lizardo K, Ayyappan JP, Ganapathi U, Dutra WO, Qiu Y, Weiss LM, Nagajyothi JF Abstract Chagas disease is caused by Trypanosoma cruzi which is endemic in Latin America. T. cruzi infection results in a latent infection with approximately a third of latently infected patients developing chronic Chagas cardiomyopathy (CCM). CCM is a common cause of cardiomyopathy in endemic regions and has a poor prognosis compared to other cardiomyopathies. The factors responsible for the transition from the asymptomatic indeterminate latent stage of infection to CCM are poorly understood. Our previous studies demonstrated th...
Source: Disease Markers - Category: Laboratory Medicine Tags: Dis Markers Source Type: research
This study provides strong evidence that following a healthy lifestyle can substantially extend the years a person lives disease-free." Commentary on Recent Evidence for Cognitive Decline to Precede Amyloid Aggregation in Alzheimer's Disease https://www.fightaging.org/archives/2020/01/commentary-on-recent-evidence-for-cognitive-decline-to-precede-amyloid-aggregation-in-alzheimers-disease/ I can't say that I think the data presented in the research noted here merits quite the degree of the attention that it has been given in the popular science press. It is interesting, but not compelling if its role...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
(BEIJING) — Seventeen more people in central China have been diagnosed with a new form of viral pneumonia that has killed two patients and placed other countries on alert as millions of Chinese travel for Lunar New Year holidays. In total, 62 cases of the novel coronavirus have been identified in the city of Wuhan, where the virus appears to have originated. The Wuhan Municipal Health Commission reported the new cases in a statement Sunday. Nineteen of those individuals have been discharged from the hospital, while two men in their 60s — one with severe preexisting conditions — have died from the illness....
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized China onetime Source Type: news
The spread of the pneumonialike illness comes ahead of the Lunar New Year, when hundreds of millions will travel.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Coronavirus (2019-nCoV) Viruses China Wuhan (China) Lunar New Year SARS (Severe Acute Respiratory Syndrome) Source Type: news
China will step up efforts to contain the coronavirus outbreak in Wuhan ahead of the Lunar New Year holidays as a rise in confirmed cases fanned fears the virus could spread to other countries.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
Chinese authorities and the World Health Organization (WHO) say a new strain of coronavirus is behind the outbreak of pneumonia in the central city of Wuhan, which has erupted just ahead of the Lunar New Year, the country's biggest festival.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
(Natural News) If you’re under the age of 18 and your parents won’t let you get vaccinated, then they must hate you and want you to die. This is what WikiHow is telling children, anyway, in a new “learn how to do anything” information page that teaches young ones how to secretly get vaccinated without...
Source: NaturalNews.com - Category: Consumer Health News Source Type: news
In this study, we were able to demonstrate that our measure for mosquito-borne viral suitability is informative in the context of Myanmar, despite the lack of ento-epidemiological datasets with high spatio-temporal resolution. By estimating suitability through climate variables and known ento-epidemiological parameters, we were able to project mosquito-born virus (MBV) suitability at the district level, a resolution for which epidemiological data and mosquito abundance measures are not generally available. Here, we discuss the national and subnational public health and control implications for MBVs in the context of our pr...
Source: PLOS Currents Outbreaks - Category: Epidemiology Authors: Source Type: research
DAVID E. BLOOM is the Clarence James Gamble Professor of Economics and Demography, DANIEL CADARETTE is a research assistant, and JP SEVILLA is a research associate, all at Harvard University’s T.H. Chan School of Public Health.By David E. Bloom, Daniel Cadarette and JP SevillaWASHINGTON DC, Jul 3 2018 (IPS)Infectious diseases and associated mortality have abated, but they remain a significant threat throughout the world.We continue to fight both old pathogens, such as the plague, that have troubled humanity for millennia and new pathogens, such as human immunodeficiency virus (HIV), that have mutated or spilled over ...
Source: IPS Inter Press Service - Health - Category: International Medicine & Public Health Authors: Tags: Active Citizens Development & Aid Economy & Trade Global Headlines Health TerraViva United Nations Source Type: news
In conclusion, the old literature on arboviruses in Mozambique is relevant for assessing the gaps and current risk of occurrence of these pathogens at the region, particularly in a time in which they are spreading worldwide. PMID: 29845522 [PubMed - in process]
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research
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