Repeat-containing effectors of filamentous pathogens and symbionts.

Repeat-containing effectors of filamentous pathogens and symbionts.
Curr Opin Microbiol. 2018 Jun 18;:
Authors: Ma LS, Pellegrin C, Kahmann R
Abstract
Pathogenic and symbiotic filamentous microbes secrete effectors which suppress host immune responses and promote a successful colonization. Pathogen effectors are engaged in the arms race with their hosts and because of this they are subject to intense evolutionary pressure. Effectors particularly prone to rapid evolution display repeat-containing domains which can easily expand or contract and accumulate point mutations without altering their original function. In this review we address the diversity of function in such repeat-containing effectors, focus on new findings and point out avenues for future work.
PMID: 29929732 [PubMed - as supplied by publisher]

Source: Current Opinion in Microbiology - June 18, 2018 Category: Microbiology Authors: Ma LS, Pellegrin C, Kahmann R Tags: Curr Opin Microbiol Source Type: research