Adenoviral Vector-Induced Silencing of RGMa Attenuates Blood-Brain Barrier Dysfunction in a Rat Model of MCAO/Reperfusion.

CONCLUSIONS: RGMa may be involved in I/R injury associated with BBB dysfunction via the CDC-42/PAK-1 signal pathway and may be a promising therapeutic target for I/R injury.
PMID: 29935233 [PubMed - as supplied by publisher]

Source: Brain Research Bulletin - June 20, 2018 Category: Neurology Authors: Li M, Wen Y, Zhang R, Xie F, Zhang G, Qin X Tags: Brain Res Bull Source Type: research