Clinical and prognostic significance of Raf kinase inhibitory protein expression in gastrointestinal stromal tumors.
CONCLUSION: This study demonstrated that: (1) RKIP expression in GISTs is associated with tumor size, NIH risk grade, and mucosal invasion, and low or no expression of RKIP predicts a high malignancy potential; (2) high RKIP correlates positively with the survival of patients with GISTs; and (3) RKIP expression has appreciated value for predicting the survival of patients with GISTs, although it is not an independent prognostic factor in GISTs.
PMID: 29930472 [PubMed - in process]
Source: World Journal of Gastroenterology - Category: Gastroenterology Authors: Wang Y, Chen JJ, Wang XF, Wang Q Tags: World J Gastroenterol Source Type: research