Bioactivities of Ethanolic Extracts of Three Parts (Wood, Nutmeg and Mace) from Myristica fragrans Houtt.

Conclusion: The extracts obtained from wood of M. fragrans showed high anti-inflammatory and anti-allergic activities but moderate anti-oxidant. The extracts of nutmeg and mace presented high anti-oxidant and anti-allergic activities but less antiinflammatory activity. Therefore, extract of wood should be selected for treatment of diseases that related with inflammation while the extracts of nutmeg and/or mace should be used as an antioxidant. Finally, extracts of all 3 parts of M. fragrans could be used for allergy-related diseases because all parts showed potent activity in anti-allergy, anti-inflammatory and antioxidant roles. However, the further study should be performed in animal models for investigation of each activity of active compounds following bioassay guided isolation. PMID: 29926690 [PubMed - in process]
Source: Journal of the Medical Association of Thailand = Chotmaihet thangphaet - Category: General Medicine Tags: J Med Assoc Thai Source Type: research