Bioactivities of Ethanolic Extracts of Three Parts (Wood, Nutmeg and Mace) from Myristica fragrans Houtt.
Conclusion: The extracts obtained from wood of M. fragrans showed high anti-inflammatory and anti-allergic activities but moderate anti-oxidant. The extracts of nutmeg and mace presented high anti-oxidant and anti-allergic activities but less antiinflammatory activity. Therefore, extract of wood should be selected for treatment of diseases that related with inflammation while the extracts of nutmeg and/or mace should be used as an antioxidant. Finally, extracts of all 3 parts of M. fragrans could be used for allergy-related diseases because all parts showed potent activity in anti-allergy, anti-inflammatory and antioxidant roles. However, the further study should be performed in animal models for investigation of each activity of active compounds following bioassay guided isolation. PMID: 29926690 [PubMed - in process]
Date: Monday, 11 18, 2019; Speaker: Barton Haynes, M.D., Frederic M. Hanes Professor of Medicine and Immunology, Duke University School of Medicine; Carolyn Coyne, Ph.D., Professor of Pediatrics, University of Pittsburgh; Matthias Gromeier, M.D., Professor of Neurosurgery, Duke University School of Medicine; Adam Zlotnick, Ph.D., Professor of Molecular and Cellular Biochemistry, Indiana University; Malcolm Martin, M.D., Chief, Laboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases; Lipsett Auditorium of the Clinical Center
Publication date: Available online 22 June 2019Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Luisa Taylor, Morgan Waller, Jay PortnoyAbstractTelemedicine (TM) involves the use of technology to provide medical services to patients who live at a distance. It can be used asynchronously for interpretation of tests (spirometry, skin tests imaging studies), and for communication of information when the simultaneous presence of provider and patient is unnecessary. Synchronous encounters can be either unscheduled and initiated on-demand by patients or they can be facilitated substitutes for in-perso...
Publication date: Available online 22 June 2019Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Stephen Betschel, Ernie Avilla, Amin Kanani, Monika Kastner, Paul Keith, Karen Binkley, Gina Lacuesta, Rozita Borici-Mazi, Jacquie Badiou, Anne Rowe, William H. Yang, Susan WasermanAbstractBackgroundHAE patients present to the emergency department (ED), where their symptoms are often incorrectly attributed to common allergic and gastrointestinal conditions resulting in major delays in diagnosis and treatment.ObjectiveThe goal of this study was to develop a rapid triage HAE tool for ED settings.Method...
ConclusionOur data support the concept of MDH as a distinct and rare subgroup of DH. The prevalence in our database was 2.5% in the total DH alleged patient population and 0.5% of the demonstrated DH. Skin testing and DPT are mandatory for confirming the diagnosis.
ConclusionLong-term Abatacept therapy is effective in the majority of patients with LRBA deficiency.
Higher intake of gluten early in life is associated with an increased risk of celiac disease (CD) and CD autoimmunity, according to new findings.Reuters Health Information
Conditions: Child Development; Growth; Allergy; Overweight; Infectious Disease; Noncommunicable Diseases Intervention: Sponsors: Helsinki University; Business Finland; Valio Ltd; Finnish Red Cross; DuPont Nutrition and Health; Oriola Corporation; Pikkujätti Medical Centre for Children and Youth Active, not recruiting
Allegations that breast implants can trigger cancer have been made in the UK since 2011. Pictured, Julie Harris is one of some 250 women suing Allergan Biocell after they claim implants caused cancer.
Conclusions: COS showed anti-allergy properties by regulating the levels of Th1 and Th2 cytokines.Int Arch Allergy Immunol
Several human polyomaviruses, including Merkel cell polyomavirus, have been isolated on the skin. Which are associated with cutaneous disease, and what do we know about their molecular mechanisms?The British Journal of Dermatology