Microbiology and prognosis assessment of hospitalized patients with aspiration pneumonia: a single-center prospective cohort study.

Microbiology and prognosis assessment of hospitalized patients with aspiration pneumonia: a single-center prospective cohort study. Infez Med. 2018 Jun 01;26(2):103-114 Authors: Papadopoulos D, Bader I, Gkioxari E, Petta V, Tsaras T, Galanopoulou N, Archontouli MA, Diamantea F, Kastanakis E, Karagianidis N, Filaditaki V Abstract Aspiration pneumonia has a high incidence in hospitalized patients with community-acquired pneumonia and results in high mortality rates. We aimed to evaluate microbiology and assess prognostic factors of aspiration pneumonia in the setting of a tertiary hospital pulmonology department. Community-acquired (CAAP) and healthcare-associated aspiration pneumonia (HCAAP) cases hospitalized over a period of a year were prospectively followed. Demographic, clinical, biological and radiological data were recorded at admission, while sputum, tracheal aspirates or bronchial washing samples were collected within 48 hours of admission. During hospital stay, therapeutic and supportive measures and resulting complications were recorded. Regression analysis was applied to find statistically significant prognostic factors. The sample consisted of 70 patients (67.1% men); 55.7% of them presented as HCAAP; 94.3% had positive culture of lower respiratory tract specimens with isolation of 115 pathogens, 47 of which were multidrug- or extensively drug-resistant. The most common pathogens were Pseudomonas aeruginosa (37.1%), Klebs...
Source: Infezioni in Medicina - Category: Infectious Diseases Tags: Infez Med Source Type: research