A Novel Microflow Phantom Dedicated to Ultrasound Microvascular Measurements.

We report a novel device for robust and stable microflow measurements and the study of the microvascularization. Based on microfluidics technology, the prototype features wall-less cylindrical channels of diameters ranging from as small as 147 up to 436 µm, cast in a soft silicone polymer and perfused via a microfluidic flow pressure controller. The device was assessed using flow rates from 49 to 146 µL/min, with less than 1% coefficient of variation over three minutes, corresponding to velocities of 6 to 142 mm/s. This enabled us to evaluate and confirm the reliability of the Superb Microvascular Imaging Doppler mode compared with the Power Doppler mode at these flow rates in the presence of vibrations mimicking physiological motion.
PMID: 29923458 [PubMed - as supplied by publisher]

Source: Ultrasonic Imaging - June 24, 2018 Category: Radiology Tags: Ultrason Imaging Source Type: research