High-Dose Rate Endobronchial Brachytherapy for Post-Transplant Bronchial Stenosis- An Interdisciplinary Effort to Initiate a New Program

Recurrent granulation tissue or anastomotic stenosis cause major morbidity for patients undergoing lung transplantation. Common therapeutic options include bronchoscopic interventions (BI) like surgical debridement, cryotherapy, LASER coagulation, balloon bronchoplasty and stent placement. Small institutional experiences have suggested efficacy of endobronchial brachytherapy (EBB) for recurrent post-transplant bronchial stenosis (PTBS) which has an anti-inflammatory effect similar to it's use for keloids or heterotopic ossification.

Source: Brachytherapy - June 23, 2018 Category: Cancer & Oncology Authors: Pranshu Mohindra, Byongyong Yi, Irina Timofte, Donnica Major, Sharrief McGee, Narottam Lamichhane, Kimberly Marter, Christine Kada, Ashutosh Sachdeva, Edward M. Pickering, Steven J. Feigenberg, Aldo Iacono Source Type: research