Acute Toxicity and Health Related Quality of Life Outcomes in a Prospective Phase II Trial of MRI-guided High Dose-Rate Brachytherapy for Localized Prostate Cancer

High dose-rate brachytherapy (HDR-BT) combined with external beam radiotherapy (EBRT) is a widely accepted method of dose escalation in the treatment of localized prostate cancer. The use of magnetic resonance imaging (MRI) to guide needle placement and for planning, enables optimal delineation of the prostate and organs at risk (OAR), potentially improving the treatment ’s therapeutic index. Herein we report early toxicity and health related quality of life (HRQoL) outcomes of a phase II clinical trial of MRI-guided prostate HDR-BT combined with EBRT.

Source: Brachytherapy - June 23, 2018 Category: Cancer & Oncology Authors: Noelia Sanmamed, Peter Chung, Alejandro Berlin, Jette Borg, Bernadeth Lao, Robert Weersink, Alex Rink, Akbar Beiki-Ardakani, Cynthia Menard, Joelle Helou Source Type: research