The Effect of Lysophosphatidic Acid (LPA) on Contractions in Equine Myometrium During the Stages of Fibrosis at the Early and Mid-luteal Phase of the Estrous Cycle

Endometrosis of equine endometrium comprises severe fibrosis and is mentioned as the main cause of the embryonic or fetal loss. Endometrosis is evidenced by morphologic and physiological alterations in the endometrium, and recently we have reported fibrosis to affect the secretory function of endometrium. However, the fibrosis effect on myometrium function is unclear. Contractions of myometrium and embryo movement during the early stage of pregnancy are mechanisms involved in the maternal recognition of pregnancy in mares.
Source: Journal of Equine Veterinary Science - Category: Veterinary Research Authors: Source Type: research