Ellipsoid zone mapping and outer retinal assessment in stargardt disease

Purpose:
To quantify and correlate ellipsoid zone and photoreceptor outer segment changes with visual acuity in Stargardt disease.
Methods:
An institutional review board–approved study of 32 eyes with Stargardt disease was performed. After spectral domain optical coherence tomography, the macular cube was exported into a novel analysis tool and volumetric assessment from the ellipsoid zone to the retinal pigment epithelium was performed. Using this information, mapping was completed with en face representation of the height between the ellipsoid zone and retinal pigment epithelium. This analysis provided quantification of ellipsoid zone and photoreceptor outer segments, including atrophy (ellipsoid zone to retinal pigment epithelium thickness = 0 μm) and attenuation (ellipsoid zone to retinal pigment epithelium thickness

Source: RETINA - June 22, 2018 Category: Opthalmology Tags: Original Study Source Type: research