Pulmonary Langerhans cell histiocytosis: the many faces of presentation at initial CT scan

Conclusions The radiologist should be familiar with PLCH imaging features to correctly diagnose the disease or need for further investigation. Teaching Points • PLCH is a rare interstitial smoking-related disease that usually affects young adults. • The typical first CT shows a mix of nodules, cavitary nodules and cysts in the upper-middle lungs. • Atypical appearance, either cysts or nodules alone, mandates that other diagnoses be considered. • Lung cystic involvement correlates with lung function abnormalities and predicts functional decline. • Integration of the clinical history and imaging results is key to diagnosis.
Source: Insights into Imaging - Category: Radiology Source Type: research