A systematic review and meta-analysis of clinicopathologic factors linked to oncologic outcomes for renal cell carcinoma with tumor thrombus treated by radical nephrectomy with thrombectomy

Renal cell carcinoma (RCC) represents 2-3% of all cancers in adults worldwide, and has an annual increase of around 2% in incidence during the past two decades [1]. Improved diagnostics have resulted in the increasing discovery of low stage renal tumors. Involvement of the venous system is a clinical characteristic of advanced RCC, which is observed in 4-10% of all RCC patients [2]. Radical nephrectomy with thrombectomy (RNTE) is the only curative therapeutic modality for these patients [3]. However, despite the aggressive resection was performed, the long-term survival of RCC with tumor thrombus (TT) remains poor compared to localized RCC.
Source: Cancer Treatment Reviews - Category: Cancer & Oncology Authors: Tags: Systematic or Meta-analysis Studies Source Type: research