Synergistic Cytokine Effects as Apremilast Response Predictors in Patients With Psoriasis

•Based on nonlinear multivariate algorithms, IL-17F is the most important predictor of PASI improvement with apremilast, and nonlinear synergistic cytokine effects are more predictive of PASI response to apremilast than linear univariate models.

Source: Journal of Allergy and Clinical Immunology - June 21, 2018 Category: Allergy & Immunology Authors: Sandra Garcet, Kristine Nograles, Joel Correa da Rosa, Peter H. Schafer, James G. Krueger Source Type: research