Imaging Cobalamin Uptake within Malignant Breast Tumors In Vivo

ConclusionThe uptake of Cbl within malignant breast tumors can be imaged clinically. Cbl uptake is greatest in TN and HER2-positive breast tumors. A solitary bolus of AC or DEX increases the [111In]AC uptake within a breast tumorin vivo. Investigating the cytogenetic mechanisms controlling the endocytosis of Cbl in malignant breast tumors is warranted.

http://link.springer.com/10.1007/s11307-018-1232-9

Source: Molecular Imaging and Biology - June 21, 2018 Category: Molecular Biology Source Type: research