Comment on "Sterilizing immunity in the lung relies on targeting fungal apoptosis-like programmed cell death"

Shlezinger et al. (Reports, 8 September 2017, p. 1037) report that the common fungus Aspergillus fumigatus, a cause of aspergillosis, undergoes caspase-dependent apoptosis-like cell death triggered by lung neutrophils. However, the technologies they used do not provide reliable evidence that fungal cells die via a protease signaling cascade thwarted by a fungal caspase inhibitor homologous to human survivin.

Source: ScienceNOW - June 21, 2018 Category: Science Authors: Aouacheria, A., Cunningham, K. W., Hardwick, J. M., Palkova, Z., Powers, T., Severin, F. F., Vachova, L. Tags: Immunology, Microbiology t-comment Source Type: news