PD-001Endoscopic prediction of tumor invasion depth in early gastric signet ring cell carcinoma

Introduction: Endoscopic resection of early gastric cancer (EGC) is now widely accepted in many countries, especially in Korea and Japan. Endoscopic resection is often preferred over surgical resection due to better quality of life. signet ring cell carcinoma (SRC) is categorized as undifferentiated or a diffuse type, endoscopic treatment was originally not considered in early gastric SRC. However, recent studies have proven excellent prognosis of early gastric signet ring cell carcinoma with fewer lymph node (LN) metastasis. Thus, some now regard early gastric SRC as a condition for endoscopic treatment. However, many of them still do not accept endoscopic treatment of SRC due to several reasons. Depth prediction scoring systems have been developed based on the endoscopic features of all histologic types including differentiated and undifferentiated cancer. However, the same endoscopic criteria may not be applied to SRC due to different biological characteristics. We, therefore, evaluated the endoscopic features of M and SM cancers in early gastric SRCs.
Source: Annals of Oncology - Category: Cancer & Oncology Source Type: research