Ultrasound Molecular Imaging of VEGFR-2 in Clear-Cell Renal Cell Carcinoma Tracks Disease Response to Antiangiogenic and Notch-Inhibition Therapy

Conclusion This study demonstrates that MI can track disease progression and assess functional changes in tumors before changes in volume are apparent, and thus, CEUS can be a valuable tool for assessing response to therapy in disease. Future work is required to determine whether levels of VEGFR-2 targeting correlate with eventual survival outcomes.

Source: Theranostics - June 20, 2018 Category: Molecular Biology Authors: Juan D. Rojas, Fanglue Lin, Yun-Chen Chiang, Anna Chytil, Diana C. Chong, Victoria L. Bautch, W. Kimryn Rathmell, Paul A. Dayton Tags: Research Paper Source Type: research