Dual-Energy CT Imaging of Tumor Liposome Delivery After Gold Nanoparticle-Augmented Radiation Therapy
Conclusions: The addition of vascular-targeted AuNPs significantly improved the treatment effect of liposomal doxorubicin after RT, consistent with the increased liposome accumulation observed in tumors in the imaging study. Using this approach with a liposomal drug delivery system can increase specific tumor delivery of chemotherapeutics, which has the potential to significantly improve tumor response and reduce the side effects of both RT and chemotherapy.
Source: Theranostics - Category: Molecular Biology Authors: Jeffrey R. Ashton, Katherine D. Castle, Yi Qi, David G. Kirsch, Jennifer L. West, Cristian T. Badea Tags: Research Paper Source Type: research
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