Adipocyte-Derived Exosomal MiR-27a Induces Insulin Resistance in Skeletal Muscle Through Repression of PPAR γ
Conclusions: These results identify a novel crosstalk signaling pathway between adipose tissue and skeletal muscle in the development of insulin resistance, and indicate that adipose tissue-derived miR-27a may play a key role in the development of obesity-triggered insulin resistance in skeletal muscle.
Source: Theranostics - Category: Molecular Biology Authors: Yang Yu, Hongwei Du, Shengnan Wei, Linjing Feng, Junnan Li, Fan Yao, Ming Zhang, Grant M. Hatch, Li Chen Tags: Research Paper Source Type: research
More News: Child Development | Children | Diets | Eating Disorders & Weight Management | Genetics | Grants | High Fat | Insulin | Nutrition | Obesity