An azobenzene-based heteromeric prodrug for hypoxia-activated chemotherapy by regulating subcellular localization

Chem. Commun., 2018, Accepted Manuscript DOI: 10.1039/C8CC03430C, CommunicationShiying Li, Xueyan Jiang, Rongrong Zheng, Shengjia zuo, Linping Zhao, Guiling Fan, Jinghao Fan, Yonghua Liao, Xiyong Xu, Hong Cheng An azobenzene-based heteromeric prodrug (hNDP) was prepared for targeted chemotherapy against hypoxic tumor. hNDP could divert the parent drug from nucleus to cytoplasm with lower toxicity. While the azoreduction of... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Chem. Commun. latest articles - Category: Chemistry Authors: Source Type: research