In This issue

Proliferative glomerulonephritis with monoclonal Ig deposits (PGNMIDs) is a  monoclonal gammopathy of renal significance that is difficult to treat and has a poor prognosis. In a series of 19 patients with well-characterized PGNMID, Gumber et al., working with hematologists, found that a hematological approach to these patients was beneficial. An underlying paraprotein was found in 37% of cases and the (presumably) responsible B or plasma cell clone was found in one-third of patients. Clone-directed hematological protocols were used not only in these patients, but were also used empirically in patients in whom a clone or paraprotein could not be detected.
Source: Kidney International - Category: Urology & Nephrology Tags: In This Issue Source Type: research