Stress aggravates high-fat-diet-induced insulin resistance via a mechanism that involves the amygdala and is associated with changes in neuroplasticity

Conclusions: Stress aggravates HFD-induced insulin resistance and neuroadaptation in the amygdala. The HFD-induced insulin resistance is amygdala-dependent. Understanding the role of stress-induced amygdalar adaptation in the development of T2D could inform therapies aimed at reducing chronic stressors to decrease the risk for T2D.
Source: Neuroendocrinology - Category: Endocrinology Source Type: research