GSE100261 Transcriptional impact of MTHFD2 in Human Aortic Endothelial Cells

Contributors : Juliane Hitzel ; Eunjee Lee ; Jun Zhu ; Ralf P BrandesSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensWe performed transcriptome analysis of Human Aortic Endothelial Cells after siRNA mediated knockdown of MTHFD2. We identified MTHFD2 as a key driver for a gene cluster which integrates mitochondrial one-carbon metabolism, serine synthesizing enzymes as well as common amino acid and ER stress response genes.

Source: GEO: Gene Expression Omnibus - June 19, 2018 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research