Early fibrinogen concentrate therapy for major haemorrhage in trauma (E-FIT 1): results from a UK multi-centre, randomised, double blind, placebo-controlled pilot trial

There is increasing interest in the timely administration of concentrated sources of fibrinogen to patients with major traumatic bleeding. Following evaluation of early cryoprecipitate in the CRYOSTAT 1 trial,...
Source: Critical Care - Category: Intensive Care Authors: Tags: Research Source Type: research

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Conditions:   Anxiety Disorders;   Oral Disease;   Periodontal Diseases;   Periodontal Attachment Loss;   Periodontal Pocket;   Periodontal Inflammation;   Gingival Recession;   Gingival Bleeding;   Gingival Diseases;   Bruxism;   Caries,Dental;   Health Care Seeking Behavior;   Healt h Care Utilization;   Self-Perception Intervention:   Sponsor:   Ain Shams University Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
ConclusionsIn patients aged ≥ 85 years with moderate-severe dementia and AF, oral anticoagulation was significantly associated with a lower embolic risk and a higher bleeding risk, with no differences in total mortality.ResumenIntroducción y objetivosEl envejecimiento de la población se asocia con una prevalencia creciente de fibrilación auricular (FA) y demencia. Con este estudio se pretende analizar el impacto de la anticoagulación oral en pacientes ancianos con FA y demencia de grado moderado-grave.MétodosEstudio retrospectivo unicéntrico que analiza a pacientes de edad ≥&...
Source: Revista Espanola de Cardiologia - Category: Cardiology Source Type: research
TUESDAY, Feb. 18, 2020 -- Progesterone may be beneficial for women with early pregnancy bleeding and a history of miscarriage, according to two studies published online Jan. 30 in the American Journal of Obstetrics&Gynecology and BJOG: An...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news
ConclusionThe results of this study showed that the pain is more observable in cold temperament group, therefore we can empower the gynecologists, midwives and nurses in this field by practical training for them and accordingly contribute to reduce the use of chemical drugs by women with primary dysmenorrhea as well as increasing their efficacy in daily activities and improving their quality of life and their physical and mental health.
Source: Clinical Epidemiology and Global Health - Category: Epidemiology Source Type: research
Since April 2014 three of Scotland's four pre-hospital trauma teams have used a unified national Code Red protocol that can be activated prior to a patient with major or massive haemorrhage arriving in the Emergency Department (ED) and which asks them to consider the following factors in order to decide whether to activate the National pre-hospital Code Red protocol; 1. Suspected or confirmed bleeding, 2. Systolic blood pressure
Source: Injury - Category: Orthopaedics Authors: Source Type: research
This study aims to evaluate radiation exposure in patients with complete portal vein thrombosis (CPVT) or portal cavernoma (PC) undergoing transjugular intrahepatic portosystemic shunt (TIPS) creation using real-time ultrasound guidance for portal vein targeting.Materials and methodsThis is a single institution retrospective analysis. Between August 2009 and September 2018, TIPS was attempted in 49 patients with CPVT or PC. Radiation exposure (dose area product [DAP], air KERMA (AK) and fluoroscopy time [FT]), technical success, clinical success, complications and survival were analyzed.ResultsIn total, 29 patients had CPV...
Source: La Radiologia Medica - Category: Radiology Source Type: research
Conclusion: Inpatient VCE is an effective tool to identify patients who need specific therapeutic interventions. Patients with negative VCE are unlikely to be readmitted or require specific therapeutic interventions in the index admission.
Source: The Saudi Journal of Gastroenterology - Category: Gastroenterology Authors: Source Type: research
AbstractBackgroundSmall bowel capsule endoscopy (SBCE) is the gold standard for suspected small bowel bleeding (SBB). Angioectasias are the most common vascular anomalies in the gastrointestinal tract and have been reported as the source of SBB in up to 80% of patients. Considering their frequency, their usual intermittent bleeding nature, and their risk of rebleeding, the aim of this study was to identify some features and possible predictors of rebleeding in the presence of these lesions.MethodsThis is a retrospective study, which included consecutive SBCE with angioectasias between April 2008 and December 2017 with a mi...
Source: Digestive Diseases and Sciences - Category: Gastroenterology Source Type: research
AbstractBackgroundRecurrent bleeding from an intracranial aneurysm after subarachnoid hemorrhage (SAH) is associated with unfavorable outcome. Recurrent bleeding before aneurysm occlusion can be performed occurs in up to one in five patients and most often happens within the first 6 h after the primary hemorrhage. Reducing the rate of recurrent bleeding could be a major factor in improving clinical outcome after SAH. Tranexamic acid (TXA) reduces the risk of recurrent bleeding but has thus far not been shown to improve functional outcome, probably because of a higher risk of delayed cerebral ischemia (DCI). To reduce the r...
Source: Trials - Category: Research Source Type: clinical trials
ConclusionsRobotically assisted mitral valve repair was feasible, safe, and therapeutically effective in the first 100 cases, with a minimal learning curve. The robotically assisted approach provides a high-quality surgical view and tremorless suture/cut handling, which will contribute to further development of minimally invasive mitral valve surgery.
Source: General Thoracic and Cardiovascular Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
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