Sex Differences at the Time of Myectomy in Hypertrophic Cardiomyopathy [Original Articles]

Conclusions:
Female patients with HCM are older at the time of myectomy and show greater impairment of diastolic function. Furthermore, left ventricular and left atrial remodeling is increased in women when corrected for body surface area. At a cellular level, HCM women showed increased compliant titin and a larger degree of interstitial fibrosis.

Source: Circulation: Heart Failure - May 31, 2018 Category: Cardiology Authors: Nijenkamp, L. L. A. M., Bollen, I. A. E., van Velzen, H. G., Regan, J. A., van Slegtenhorst, M., Niessen, H. W. M., Schinkel, A. F. L., Kruger, M., Poggesi, C., Ho, C. Y., Kuster, D. W. D., Michels, M., van der Velden, J. Tags: Contractile Function, Pathophysiology, Translational Studies, Cardiomyopathy Original Articles Source Type: research