Syntheses, crystal structures, antioxidant SOD-like properties and in-vitro antimicrobial studies of Cu(II) and Ni (II) complexes with 2-((E)-(4-bromo-2-chlorophenylimino) methyl)-6-bromo-4-nitrophenol and (E)-1-(3, 5-dichloro-2-hydroxybenzylidene)-4, 4-dimethylthiosemicarbazide

Publication date: 5 November 2018 Source:Journal of Molecular Structure, Volume 1171 Author(s): Bharti Mohan, Achintya Jana, Neeladri Das, Sulakshna Bharti, Mukesh Choudhary Three new salen-type copper (II) and nickel (II) complexes viz. [Cu(L)2] (1); [Ni(L)2] (2); [Ni(L1) (DMF)] (3), where HL = 2-((E)-(4-bromo-2-chlorophenylimino) methyl)-6-bromo-4-nitrophenol and HL1= (E)-1-(3,5-dichloro-2-hydroxybenzylidene)-4,4-dimethylthiosemicarbazide; DMF = N, N-dimethylformamide, have been successfully achieved and structurally characterized by single crystal X-ray analysis. The salen-type ligands (HL and HL1) are able to provide the most plausible geometry for 1:2 complexes which appeared to be a square planar (four coordinated) geometry around the M (II) ions. The FT-IR spectra, UV–Vis spectra and magnetic susceptibility measurements agree with the observed crystal structures. X-band Electron paramagnetic resonance (EPR) spectra indicate a dx 2 –y 2ground state (g||>g⊥> 2.0023 and A||>A⊥) for (1) at RT and LNT. The salen-type ligands were behaves as monobasic bidentate-N, O ligand (HL) or tridentate ligand (HL1) possessing N, O and S donor atoms. Electrochemical properties for complexes (1)-(3) yielded an irreversible couple that can be assigned to an M (II)/M (I) redox process. These complexes exhibit effective antioxidant activity towards the dismutation of superoxide anions. The complex (1) exhibits more active scavenging effects agains...
Source: Journal of Molecular Structure - Category: Molecular Biology Source Type: research