Scrutinizing the Expression and Blockade of Inhibitory Molecules Expressed on T Cells from Acute Myeloid Leukemia Patients.

In conclusion, our data indicate that CD4+ and CD8+ T cells from AML patients appeared to be exhausted and blockade of some immune checkpoints can improve the proliferation of those cells.
PMID: 29908544 [PubMed - in process]

Source: Iranian Journal of Allergy, Asthma and Immunology - June 1, 2018 Category: Allergy & Immunology Authors: Abdolmaleki M, Mojtabavi N, Zavvar M, Vaezi M, Noorbakhsh F, Nicknam MH Tags: Iran J Allergy Asthma Immunol Source Type: research