Doctors Think a Woman ’s Tattoo May Have Been Causing Her Severe Leg Pain

Doctors in Scotland believe a woman’s large tattoo on her leg may have been the cause of her unexplained inflammation and severe leg pain. The authors of a report on the woman’s case, published in BMJ Case Reports, say it is a reminder to physicians that they should be mindful of their patients’ tattoos if they encounter unusual and unexplained symptoms. The 31-year-old woman was suffering a condition called inflammatory myopathy, which affected her left leg and caused pain severe enough to disrupt her sleep. The woman had a double lung transplant in 2009, and was taking drugs to suppress her immune system so she would not reject the donated organ. Test after test revealed no obvious cause for her pain, and when it didn’t abate after 10 months, she had a biopsy of the thigh muscle, which finally revealed the inflammation. Doctors then speculated that a large, multi-colored tattoo she had received on the left thigh might have contributed to her condition. “Nobody had inquired about the tattoo. But given she had unusual symptoms that were otherwise unexplainable and the onset of this pathology was at the same time and location as the tattoo, that sent the bells ringing for us thinking that there was a possible link,” says Dr. William Wilson, a trauma and orthopedic surgeon at University of Glasgow, who is the lead author of the case study. Wilson says he can’t prove that the tattoo actually caused the woman’s inflammation, but s...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized healthytime onetime tattoos Source Type: news

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The immune cells of the brain are somewhat different in character and function from those of the body. They have a greater portfolio of tasks beyond chasing down pathogens, clearing out waste, and assisting in regeneration. For example, the immune cells known as microglia are involved in the maintenance of synaptic connections between neurons. Interestingly, microglia are not produced in the bone marrow by stem cells or progenitor cells, so in the research here in which young bone marrow is transplanted into old mice, one can be fairly sure that any beneficial effects on microglia result from signaling differences on the p...
Source: Fight Aging! - Category: Research Authors: Tags: Daily News Source Type: blogs
Authors: Braun OÖ, Nilsson J, Gustafsson F, Dellgren G, Fiane AE, Lemström K, Hubbert L, Hellgren L, Lund LH Abstract OBJECTIVES: The purpose of this study was to assess complications and mortality and its predictors, with continuous-flow left ventricular assist devices (CF-LVADs) in the Nordic Countries. DESIGN: This was a retrospective, international, multicenter cohort study. RESULTS: Between 1993 - 2013 442 surgically implanted long-term mechanical assist devices were used among 8 centers in the Nordic countries. Of those, 238 were CF-LVADs (HVAD or HeartMate II) implanted in patients>18 ye...
Source: Scandinavian Cardiovascular Journal - Category: Cardiology Tags: Scand Cardiovasc J Source Type: research
Authors: Najjar E, Ljung Faxén U, Hage C, Donal E, Daubert JC, Linde C, Lund LH Abstract OBJECTIVES: Soluble suppression of tumorigenecity 2 (sST2) is prognostic in acute and chronic heart failure with reduced ejection fraction (HFrEF) but less studied in HF with preserved EF (HFpEF). We evaluated sST2 concentrations, correlations with biomarkers and echocardiographic measures of diastolic and systolic function, and associations with outcomes in HFpEF and HFrEF. DESIGN AND RESULTS: A total of 193 subjects from three different cohorts were included. Eighty-six HFpEF patients were obtained from the Karolin...
Source: Scandinavian Cardiovascular Journal - Category: Cardiology Tags: Scand Cardiovasc J Source Type: research
Heart rate variability is now well-established as a means to assess autonomic nervous system (ANS) control by analyzing the beat-to-beat variability over time of consecutive heart beats. The R-R intervals are mathematically transformed and depicted as power spectra within different frequency domains. Low frequency reflects both sympathetic and parasympathetic activity, high frequency reflects parasympathetic activity, and total power reflects overall autonomic activity. These analyses have been applied to a wide range of clinical conditions, and investigators have studied maturation of ANS control in preterm and term infan...
Source: The Journal of Pediatrics - Category: Pediatrics Authors: Tags: The Editors' Perspectives Source Type: research
Kuppermann N, Ghetti S, Schunk JE, Stoner MJ, Rewers A, McManemy JK. Clinical Trial of Fluid Infusion Rates for Pediatric Diabetic Ketoacidosis. N Engl J Med 2018;378:2275-87.
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Publication date: Available online 20 February 2019Source: The Journal of Molecular DiagnosticsAuthor(s): Jennifer Tyler, Lorie Kumer, Carolyn Fisher, Heather Casey, Hiroko ShikeAbstractChimerism testing is used to monitor engraftment and risk of relapse after allogeneic hematopoietic stem cell transplant for hematological malignancy. Although short tandem repeat (STR) method is widely used among clinical laboratories, quantitative PCR (qPCR) provides better sensitivity (0.1%) than STR (1% to 5%), but is less accurate than STR for patients in mixed chimerism. qPCR chimerism test allows evaluation of residual recipient cell...
Source: The Journal of Molecular Diagnostics - Category: Pathology Source Type: research
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Source: Daily Express - Health - Category: Consumer Health News Source Type: news
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Source: Journal of surgical orthopaedic advances - Category: Orthopaedics Tags: J Surg Orthop Adv Source Type: research
Authors: Luo TD, Marois AJ, Smith TL, Willey JS, Emory CL Abstract Ascorbic acid (vitamin C) is an essential micronutrient with evidence supporting its role in bone formation, tissue repair, and collagen production. Its clinical importance to the field of orthopaedic surgery has yet to be fully defined. Several observational studies have shown improved bone density and reduced hip fracture risk with supplementation. Its effect on bone fracture and soft tissue injury has been promising in animal models, but is not adequately studied in human trials. Results have been mixed concerning its role in chondroprotection an...
Source: Journal of surgical orthopaedic advances - Category: Orthopaedics Tags: J Surg Orthop Adv Source Type: research
Due to the collapse of the price of genetic testing and the FDA’s gradual ease of the regulatory environment, direct-to-consumer (DTC) genetic testing companies are booming. You can inquire your deoxyribonucleic acid about your ancestry, health risks, metabolism, and some start-ups even promise you to find true love or your kids’ talents. As the jungle of DTC companies is getting denser, more and more people ask me which genetic tests are worth the try. They love the possibility of getting access to their DNA but don’t know where to start. Here’s the DTC genetic testing kick-starter package! Naviga...
Source: The Medical Futurist - Category: Information Technology Authors: Tags: Genomics 23andme ancestry DNA DTC future genetic test Genetic testing genetics Genome genome sequencing Health 2.0 Source Type: blogs
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