How to address the challenges of evaluating treatment benefits-risks in rare diseases? A convergent mixed methods approach applied within a Merkel cell carcinoma phase 2 clinical trial

Demonstrating treatment benefits within clinical trials in the context of rare diseases is often methodologically and practically challenging. Mixed methods research offers an approach to overcome these challe...

Source: Orphanet Journal of Rare Diseases - June 18, 2018 Category: Internal Medicine Authors: Murtuza Bharmal, Isabelle Guillemin, Alexia Marrel, Benoit Arnould, J érémy Lambert, Meliessa Hennessy and Fatoumata Fofana Tags: Research Source Type: research