Histogram Profiling of Postcontrast T1-Weighted MRI Gives Valuable Insights into Tumor Biology and Enables Prediction of Growth Kinetics and Prognosis in Meningiomas.

CONCLUSIONS: Contrary to previously reported findings, pretherapeutic postcontrast T1-weighted images can be used to predict growth kinetics in meningiomas if whole tumor histogram analysis is employed. However, no differences between distinct WHO grades were identifiable in out cohort. As a consequence, histogram analysis of postcontrast T1-weighted images is a promising approach to obtain quantitative in vivo biomarkers reflecting the proliferative potential in meningiomas. PMID: 29909365 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/29909365?dopt=Abstract

Source: Translational Oncology - June 14, 2018 Category: Cancer & Oncology Authors: Gihr GA, Horvath-Rizea D, Kohlhof-Meinecke P, Ganslandt O, Henkes H, Richter C, Hoffmann KT, Surov A, Schob S Tags: Transl Oncol Source Type: research