Lower circulating levels of angiotensin-converting enzyme (ACE) in patients with schizophrenia

This study aimed at evaluating changes in the renin-angiotensin system (RAS) in patients with schizophrenia in comparison with controls. Plasma levels of angiotensin-converting enzyme (ACE), ACE2, angiotensin (Ang)-(1 –7) and Ang II were assessed in 25 patients with schizophrenia and 20 controls. Patients with schizophrenia presented decreased levels of ACE compared to controls [median (25th–75th percentiles) = 434.79 (341.15–524.02) vs. 508.49 (396.34–608.72); p 

Source: Schizophrenia Research - June 17, 2018 Category: Psychiatry Authors: Satyajit Mohite, Salvina M. de Campos-Carli, Natalia P. Rocha, Shiva Sharma, Aline S. Miranda, Izabela G. Barbosa, Joao V. Salgado, Ana Cristina Simoes-e-Silva, Antonio L. Teixeira Source Type: research