Chemical communication between cardiac cells is disrupted by High glucose. Implications for the diabetic heart.

Conclusions: high glucose (25mM) disrupts chemical communication between cardiac cells-an effect highly dependent on PKC activation. The possible role of enhanced intracellular Ang II levels induced by high glucose on the disruption of chemical communication was discussed as well as the possible implications of these findings for the diabetic heart. PMID: 25261156 [PubMed - as supplied by publisher]
Source: Experimental Cell Research - Category: Cytology Authors: Tags: Exp Cell Res Source Type: research