Acute stroke presenting with isolated acalculia

We report the case of a 63-year-old male with a 1  day history of isolated acalculia that was found to have a left parietal lobe infarct with several smaller infarcts in the left occipital lobe.
Source: The American Journal of Emergency Medicine - Category: Emergency Medicine Authors: Source Type: research

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DISCUSSION: Our association of MYH11, FZD3, SORCS3, and GOLGA8B with dementia is supported by independent functional studies in human subjects, model systems, and associations with shared risk factors for stroke and dementia. PMID: 32966694 [PubMed - as supplied by publisher]
Source: The Journal of Alzheimers Association - Category: Psychiatry Tags: Alzheimers Dement Source Type: research
AbstractBackgroundDysphagia affects up to 30% of hospitalized patients, and it is associated with numerous complications.AimsAssess the impact of a 24/7 dysphagia screening protocol in an Internal Medicine Unit regarding respiratory complications (such as aspiration pneumonia) as the primary outcome. Length of stay and discharge destination were secondary outcomes.MethodsCase-control hospital-based analysis comparing the outcomes before and after the implementation of the screening protocol. We analysed demographic data (such as age and gender) and clinical data (presence of dysphagia, vascular risk factors and other comor...
Source: Irish Journal of Medical Science - Category: General Medicine Source Type: research
This study aims to compare how older adults with cognitive impairment perceive relevance and level of EICT challenge between eHealth use and general use. METHODS: This cross-sectional study includes 32 participants (65-85 years of age) with cognitive impairment of different origins (due to e.g., stroke or dementia). The Short Everyday Technology Use Questionnaire+ (S-ETUQ+) was used, providing information about the relevance of EICTs and measuring the EICT level of challenge. Data were analysed with descriptive statistics, standardized z-tests and Fisher's exact tests. The significance level was set to p 
Source: Disability and Rehabilitation. Assistive Technology. - Category: Rehabilitation Authors: Tags: Disabil Rehabil Assist Technol Source Type: research
This study showed an association between reduced REM and increased mortality, but it did not demonstrate the cause of the association. REM deprivation could independently contribute to the development of numerous other diseases. The results apply more clearly to older adults, given that the age groups studied averaged in the 50s and 70s. Short REM may also be a marker of a sick or aging brain; less REM sleep has already been tied to a greater risk of dementia. Overall, ensuring adequate REM sleep is important to protecting your long-term health. Getting better sleep in middle age and beyond Maintaining good sleep should re...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Brain and cognitive health Fatigue Memory Sleep Source Type: blogs
Abstract Up to 30% of stroke patients experience cognitive decline within one year of their stroke. There are currently no FDA-approved drugs that can prevent post-stroke cognitive decline, in part due to a poor understanding of the mechanisms involved. We have previously demonstrated that a B-lymphocyte response to stroke, marked by IgA+ cells, can cause delayed cognitive dysfunction in mice and that a similar adaptive immune response occurs in the brains of some human stroke patients that suffer from vascular dementia. The stimuli which trigger B-lymphocyte activation following stroke, and their target antigens,...
Source: Brain, Behavior, and Immunity - Category: Neurology Authors: Tags: Brain Behav Immun Source Type: research
SARS-CoV-2 is transmitted by droplets and likely aerosols. The median incubation period is about 5-6 days (range 1-14 days)1 and the median age at confirmed infection in Germany is 49 years. Typical symptoms include fever, cough, anosmia, ageusia, and pneumonia. The mortality rate of COVID-19 is higher among elderly and among ethnicities other than Caucasians. Furthermore, a markedly higher mortality rate has been observed for several comorbidities including obesity class II (BMI 35 •0-39•9 kg/m2) and III (BMI 40•0+ kg/m2), uncontrolled diabetes mellitus, malignancies in the previous year, severely reduced g...
Source: Journal of Infection - Category: Infectious Diseases Authors: Source Type: research
Cognitive impairment and dementia following cerebrovascular disease are increasingly common in the UK. One potential strategy to prevent post-stroke cognitive decline is multimodal vascular risk factor managem...
Source: BMC Geriatrics - Category: Geriatrics Authors: Tags: Research article Source Type: research
ydın D Abstract Diabetes contributes to neurological dysfunction including peripheral nerve diseases, stroke and dementia. We investigated the effects of diabetes on apoptosis and mitosis in the hippocampal CA1 region. Rats were given diabetes by injection of streptozotocin (STZ). The mass and blood glucose levels of the rats were measured until day 7 of the experiment. The loss of mass index was approximately 10%, and the diabetogenic index was approximately 330% between nondiabetic and diabetic groups. We investigated caspase-3, caspase-7 and Ki 67 levels immunohistochemically for mitotic activity, the TUNEL me...
Source: Biotechnic and Histochemistry - Category: Research Authors: Tags: Biotech Histochem Source Type: research
The current COVID-19 pandemic presents unprecedented new challenges to public health and medical care delivery. To control viral transmission, social distancing measures have been implemented all over the world, interrupting the access to routine medical care for many individuals with neurological diseases. Cognitive disorders are common in many neurological conditions, e.g., stroke, traumatic brain injury, Alzheimer's disease, and other types of dementia, Parkinson's disease and parkinsonian syndromes, and multiple sclerosis, and should be addressed by cognitive rehabilitation interventions. To be effective, cognitive reh...
Source: Frontiers in Neurology - Category: Neurology Source Type: research
NIH Director's Wednesday Afternoon Lecture Series The Nelson laboratory ’ s research interests include elucidating the mechanisms by which cerebral blood flow is controlled to meet the diverse and ever-changing demands of active neurons and how these mechanisms are disrupted in small vessel disease (SVD) — a major cause of stroke and dementia. Dr. Nelson and colleagues have unraveled many of the major mechanisms that control cerebrovascular function, including the discovery of local calcium signals ( “ sparks ” ), which counter-intuitively oppose vasoconstriction. They have recently shown that brai...
Source: Videocast - All Events - Category: General Medicine Tags: Upcoming Events Source Type: video
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