High expression of tumor necrosis factor receptor 2 in tissue is associated with progression and prognosis of esophageal squamous cell carcinoma

In this study, we detected TNFR2 expression in ESCC tissues using IHC. The χ2 test showed that TNFR2 was positively correlated with invasion depth, advanced clinical stage and low differentiation; survival analysis showed that TNFR2 was positively correlated with poor OS; univariate Cox regression analysis showed that clinical stage, lymph node involvement and invasion de pth were all correlated with OS; multivariate Cox regression analysis showed that lymph node involvement and invasion depth were independent prognostic factors.

Source: Human Pathology - June 16, 2018 Category: Pathology Authors: Zifeng Liu, Changgeng Ma, Guohui Ma, Xiumei Sun, Jin Liu, Shuang Li, Kang Liu, Junye Wang, Dong Yang Tags: Original contribution Source Type: research