Pharmacokinetics of a Novel Sildenafil Orodispersible Film Administered by the Supralingual and the Sublingual Route to Healthy Men

ConclusionsIn healthy men, sublingual and supralingual administration of sildenafil ODF resulted in a remarkably similar pharmacokinetic profile and confirmed the safety of both study treatments. The recently marketed sildenafil ODF, administered by both investigated routes, can provide a valuable alternative to the marketed solid oral forms (tablets) in ED treatment.

http://link.springer.com/10.1007/s40261-018-0665-x

Source: Clinical Drug Investigation - June 16, 2018 Category: Drugs & Pharmacology Source Type: research