Clinical Significance of Human Papillomavirus Type 16 for Breast Cancer & Adenocarcinomas of Various Internal Organs and Alzheimer's Brain with Increased β-amyloid (1-42); Combined Use of Optimal Doses of Vitamin D3 and Taurine 3 times/day Has Significant Beneficial Effects of Anti-Cancer, Anti-Ischemic Heart, and Memory & Other Brain Problems By Significant Urinary Excretion of Viruses, Bacteria, and Toxic Metals & Substances.

Clinical Significance of Human Papillomavirus Type 16 for Breast Cancer &Adenocarcinomas of Various Internal Organs and Alzheimer's Brain with Increased β-amyloid (1-42); Combined Use of Optimal Doses of Vitamin D3 and Taurine 3 times/day Has Significant Beneficial Effects of Anti-Cancer, Anti-Ischemic Heart, and Memory &Other Brain Problems By Significant Urinary Excretion of Viruses, Bacteria, and Toxic Metals &Substances. Acupunct Electrother Res. 2016;41(2):127-134 Authors: Omura Y Abstract Human Papillomavirus type 16 (HPV-16) has a significant role in various cancers and Alzheimer's disease. 500 breast cancer mammograms as well as 3 cases of adenocarcinomas of esophagus, stomach, colon, prostate gland, uterus, ovary that was examined had significant infection of HPV- 16 with significantly increased β- amyloid (1-42). When a strong HPV-16 infection is found in the oral cavity, repeated exposure to the infected individual's coughing can infect others easily through saliva. Just like all of above cancer tissues, all 20 Alzheimer's cases that were examined had significantly increased HPV-16 of 1500-3000ng with markedly reduced Acetylcholine of 0.5~1.5ng and significantly increased 3- amyloid (1-42) of 7.5ng or higher. Since every cancer and Alzheimer's patient examined had significantly reduced amounts of Vitamin D3 and Taurine, the author examined the effects of Vitamin D3 and Taurine independently, or by combination. Each of opti...
Source: Acupuncture and Electro-Therapeutics Research - Category: Complementary Medicine Tags: Acupunct Electrother Res Source Type: research

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From the dawn of civilization to 2003, humankind generated five exabytes [5 billion gigabytes] of data. Now we produce five exabytes every two days ... and the pace is accelerating. —Eric Schmidt, executive chairman at Google, quoted in R. Smolan and J. Erwitt, eds. 2012. The Human Face of Big Data. Against All Odds Productions. A data revolution is changing the face of science. Scientists are confronting research challenges that require the analysis of large amounts of information on topics ranging from global climate patterns to genetic blueprints. These big data challenges are often summarized in four words: ...
Source: Washington Watch - Category: Biology Authors: Source Type: news
Genome sequencing coupled with medical and personal data holds enormous promise for unraveling the mysteries of the human body and advancing disease treatment. Increasingly, research projects are collecting data on large numbers of people to determine links among diseases, lifestyle, environment, and genes. The biobanks being created with these data raise questions about protecting the privacy of individuals whose DNA and medical records fuel research. Repositories of human genetic material emerged more than a decade ago in Iceland with the company deCODE genetics. The United Kingdom has created a biobank with 500,000 enr...
Source: Washington Watch - Category: Biology Authors: Source Type: news
Publication date: 1 April 2019Source: Colloids and Surfaces B: Biointerfaces, Volume 176Author(s): Meng Xie, Feng Zhang, Houping Peng, Yanan Zhang, Yeping Li, Yuanguo Xu, Jimin XieAbstractIn this work, graphene oxide nanosheets loaded by magnetic iron oxide nanoparticles (mGO) was synthesized and the technique of layer-by-layer (LbL) self-assembly was utilized in the successful production of chitosan/sodium alginate functionalized mGO naocomposites for use in targeted anti-cancer drug delivery and photothermal therapy. The mGO-CS/SA nanocomposites had a diameter of ˜0.5 μm and a thickness of 40–60&thi...
Source: Colloids and Surfaces B: Biointerfaces - Category: Biochemistry Source Type: research
In this study, carbon xerogel nanoparticles (CX-NPs) were synthesized as a novel photothermal nanomaterial and activated upon laser light of 808-nm wavelength for cancer phototherapy application. The synthesized CX-NPs had a spherical shape with a size of about 16 nm that showed nice photothermal conversion ability. Upon light irradiation with a power density of 1.0 W cm−2 for 15 min, a temperature increment occurred. A concentration-dependent cytotoxicity was also obtained for CX-NPs toward the C540 (B16/F10) cell line upon light irradiation, while CX-NPs presented biocompatibility in the...
Source: Colloids and Surfaces B: Biointerfaces - Category: Biochemistry Source Type: research
ConclusionsThe selective antitumor behavior and the lack of toxicity, potentially make ruthenium(II) metallodendrimers promising agents for cancer therapy.Graphical abstract
Source: European Polymer Journal - Category: Chemistry Source Type: research
In this study, we designed a spherical nanodrug by forming clusters using DOX and a polymer-engineered rGO. These spherical nanodrugs had a diameter of around 750 nm and assumed both functionalities of chemical therapy and the photothermal effect. In addition, this nanodrug featured a high-loading capability of DOX, a pH-responsive release profile, a self-fluorescent capability, and an effective accumulation in cancer cells. The layer-by-layer assembly of three cycles of polyethylene glycol (PEG) and polyacrylic acid (PAA) around the rGO core was indispensable in achieving a chemically-modified rGO precursor that asse...
Source: Chinese Chemical Letters - Category: Chemistry Source Type: research
Analyst, 2019, Accepted Manuscript DOI: 10.1039/C8AN02501K, PaperQi Wang, Yuan Zhang, Xiaodong Wang, Yuehuan Wu, Chuan Dong, Shaomin Shuang A MnO2 nanoparticles (MnO2 NPs) mediated fluorescent turn-on probe for sensitively and selectively detecting glutathione (GSH) and recognizing cancer cells was established in this work. MnO2 NPs were synthesized simply... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Analyst latest articles - Category: Chemistry Authors: Source Type: research
Authors: De Pergola G, Martino T, Zupo R, Caccavo D, Pecorella C, Paradiso S, Silvestris F, Triggiani V Abstract BACKGROUND: Obesity is associated with lower serum vitamin D (25(OH)D) levels through several mechanisms. The aim of the study was to examine the possibility of a negative association between fat mass and 25(OH)D levels in a cohort of otherwise healthy overweight and obese subjects, independently of age, sex, blood pressure levels and anthropometric and metabolic parameters. MATERIALS AND METHODS: 147 overweight and obese subjects (106 women and 41 men), aged between 18 and 69 years, were enrolled in...
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - Category: Drugs & Pharmacology Tags: Endocr Metab Immune Disord Drug Targets Source Type: research
The alliances come as its merger with Bristol-Myers Squibb progresses
Source: Chemical and Engineering News - Category: Chemistry Authors: Source Type: research
Authors: Sabapati M, Palei NN, C K AK, M RB Abstract The present study was aimed to develop Annona muricata fruit extract loaded solid lipid nanoparticles (SLNs) and explore its cytotoxic potential in vitro model of breast cancers. Extract loaded SLNs was successfully prepared by high-pressure homogenization followed by ultrasonication method and optimized using 23 full factorial design. The extract loaded SLNs were characterized using different parameters such as particle size (PS), % entrapment efficiency (EE), zeta potential (ZP) and % cumulative drug release (CDR). The SLNs formulation was optimized on the basi...
Source: Drug Development and Industrial Pharmacy - Category: Drugs & Pharmacology Tags: Drug Dev Ind Pharm Source Type: research
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