Redefining systemic lupus erythematosus — SMAARTT proteomics

Redefining systemic lupus erythematosus — SMAARTT proteomicsRedefining systemic lupus erythematosus — SMAARTT proteomics, Published online: 15 June 2018; doi:10.1038/s41584-018-0035-3As the diagnosis and management of systemic lupus erythematosus (SLE) can be challenging, reclassification of SLE on the basis of biomarker data provides novel insights. Definitions of antinuclear antibodies and attention to SMAARTT criteria (specificity – sensitivity, measurable, actionable, added value, realistic, titres, timely) are needed to translate these new analytical frameworks into real-time clinical use.

Source: Nature Reviews Rheumatology - June 15, 2018 Category: Rheumatology Authors: Marvin J. Fritzler Michael Mahler Source Type: research