Type 1 diabetes

Publication date: 16–22 June 2018 Source:The Lancet, Volume 391, Issue 10138 Author(s): Linda A DiMeglio, Carmella Evans-Molina, Richard A Oram Type 1 diabetes is a chronic autoimmune disease characterised by insulin deficiency and resultant hyperglycaemia. Knowledge of type 1 diabetes has rapidly increased over the past 25 years, resulting in a broad understanding about many aspects of the disease, including its genetics, epidemiology, immune and β-cell phenotypes, and disease burden. Interventions to preserve β cells have been tested, and several methods to improve clinical disease management have been assessed. However, wide gaps still exist in our understanding of type 1 diabetes and our ability to standardise clinical care and decrease disease-associated complications and burden. This Seminar gives an overview of the current understanding of the disease and potential future directions for research and care.
Source: The Lancet - Category: General Medicine Source Type: research